Subthalamic deep brain stimulation improves smooth pursuit and saccade performance in patients with Parkinson’s disease

Table 4 Correlation values between UPDRS motor scores and oculomotor parameters

A: Smooth pursuit parameters		p-values (correlation coefficient)
	Target velocities (°/s)	DBS OFF	DBS ON
Gain	10	0.305 (−0.256)	0.131 (−0.369)
	20	0.135 (−0.366)	*0.094 (−0.406)*
	30	0.168 (−0.339)	0.527 (−0.160)
	40	0.243 (−0.310)	0.670 (−0.108)
Velocity Accuracy	10	0.150 (−0.354)	<0.001 (−0.759)
	20	0.767 (−0.075)	*0.060 (−0.452)*
	30	0.627 (−0.123)	0.532 (−0.158)
	40	0.466 ( 0.196)	0.521 (−0.162)
Latency		0.265 (−0.320)	0.828 ( 0.059)
B: Saccade parameters	p-values
	Target amplitudes (°)	DBS OFF	DBS ON
Velocity	20	0.705 (−0.099)	*0.080 (−0.423)*
	40	0.313 ( 0.252)	*0.055 (−0.460)*
	60	0.539 ( 0.166)	0.338 (−0.248)
Amplitude Accuracy	20	0.518 (−0.168)	0.048 (−0.473)
	40	0.503 ( 0.169)	0.048 (−0.473)
	60	0.905 (−0.033)	0.811 (−0.063)
Latency		0.404 ( 0.217)	0.009 (−0.614)

Table 4A Correlation values between UPDRS motor scores and smooth pursuit parameters with DBS ON and DBS OFF. The correlation coefficient values are presented within the parentheses. Table 4B. Correlation values between UPDRS scores and saccade parameters with DBS ON and DBS OFF. Bold values indicate found significant correlation (p < 0.05), italic values indicate trends of correlation (p < 0.1). A negative correlation coefficient value suggests that PD subjects with higher UPDRS scores had poorer performance in the oculomotor parameter analyzed.

ISSN: 1743-0003