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Table 1 Gait dynamics in saline-treated, MPTP-treated (90 mg/kg cumulative dose), and 3NP-treated (75 mg/kg cumulative dose) mice walking on a treadmill belt at a speed of 34 cm/s.

From: Gait dynamics in mouse models of Parkinson's disease and Huntington's disease

 

Saline (n = 7)

MPTP (n = 7)

3NP (n = 3)

Stride Length (cm)

7.1 ± 0.1

6.6 ± 0.1*

7.3 ± 0.1

Stride Frequency (Hz)

5.0 ± 0.1

5.4 ± 0.1*

4.9 ± 0.1

Stride Duration (ms)

207 ± 2

194 ± 1*

217 ± 5

% Stance Duration

54.3 ± 0.9

55.9 ± 1.1

59.4 ± 2.3*

% Swing Duration

45.7 ± 0.9

44.1 ± 1.1

40.6 ± 2.3*

Forelimb Stance Width (cm)

1.7 ± 0.1

1.6 ± 0.1

1.7 ± 0.1

Forelimb Paw Placement Angle (°)

2.6 ± 0.6

2.6 ± 0.4

3.5 ± 1.1

Hind limb Stance Width (cm)

2.4 ± 0.2

2.2 ± 0.1

2.8 ± 0.2

Hind limb Paw Placement Angle (°)

13.9 ± 1.6

10.8 ± 1.3

15.2 ± 1.0

  1. Means ± SE. *P < 0.05, compared to saline-treated mice.