Admission day With anti-PD medication | Without anti-PD medication | Comparison between DBS OFF and ON | |||
---|---|---|---|---|---|
DBS ON | DBS OFF | DBS ON | Median difference | p-value | |
Md (q1–q3) range | Md (q1–q3) range | Md (q1–q3) range | Md (q1–q3) range | ||
Timed tests | |||||
10 m walk test, gaitspeed (m/s) | 1.3 (1.1–1.4) 1.0–1.7 | 0.91 (0.74–1.3) 0.38–1.4 | 1.3 (1.1–1.4) 0.71–1.4 | 0.30 (0.00–0.49) -0.06–0.73 | 0.016 (2 ties) |
Chair-stand test (s) | 15.0 (12.5–17.5) 10.0–23.0 | 18.5 (16.3–22.5)1 13.0–24.0 | 14.5 (12.0–18.8)1 12.0–21.0 | 3.5 (3.0–5.0) 1.0–6.0 | 0.0081 |
Timed Up & Go (s) | 10.0 (8.5–11.0) 7.0–12.0 | 11.0 (11.0–18.5)2 8.0–29.0 | 9.0 (8.5–11.0)2 7.0–17.0 | 3.0 (1.5–8.5) 0.00–12.0 | 0.0082 (1 tie) |
One leg stance (s) | 20.5 (7.3–56.3) 2.0–60.0 | 11.0 (7.8–15.0) 3.0–29.0 | 25.5 (14.8–36.5) 3.0–47.0 | 11.5 (6.3–17.5) -7.0–39.0 | 0.006 |
Sharpened Romberg (s) (eyes open) | 32.5 (17.0–60.0) 5.0–60.0 | 14.0 (6.5–27.8) 2.0–60.0 | 26.5 (17.0–55.5) 5.0–60.0 | 11.5 (-3.3–32.0) -9.0–55.0 | 0.051 |
Sharpened Romberg (s) (eyes closed) | 8.0 (5.8–19.3) 2.0–32.0 | 4.5 (2.0–12.5) 1.0–25.0 | 3.0 (3.0–8.5) 2.0–14.0 | 1.0 (-6.3–2.3) -22.0–4.0 | > 0.3 |
BBS | 49.5 (43.8–51.5) 40.0–54.0 | 42.0 (34.5–48.0) 27.0–50.0 | 50.0 (46.8–52.0) 41.0–52.0 | 6.0 (2.8–12.5) 1.0–21.0 | 0.002 |
FES (S) Total score | 52.5 (31.5–65.0) 3.0–95.0 | 111.0 (84.5–127.3) 52.0–130.0 | 53.5 (30.3–75.5) 21.0–100.0 | 0.002 |