Table 3 Mean (SEM) baseline clinical scores and baseline kinetic and kinematic variables for subjects in the combined locomotor treadmill training and Tizanidine (TizLTT) and locomotor treadmill training alone (LTT) groups that did and did not achieve the minimal important difference (MID) for walking speed (10MWT)
Group | TizLTT | LTT | |||||
|---|---|---|---|---|---|---|---|
Test | MID achieved | MID not achieved | P-value | MID achieved | MID not achieved | P-value | |
WISCI II score | 18.9 (0.9) | 14.3 (1.1) | <0.01 | 16.0 (3.5) | 14.4 (1.2) | 0.70 | |
10MWT speed (m/s) | 0.8 (0.1) | 0.4 (0.1) | 0.02 | 1.1 (0.3) | 0.5 (0.1) | 0.01 | |
6MWT distance (m) | 280.5 (30.8) | 154.6 (35.8) | 0.02 | 364.5 (92.8) | 171.6 (28.1) | 0.02 | |
TUG time (s) | 15.0 (1.9) | 51.8 (12.5) | 0.01 | 12.1 (3.1) | 45.1 (9.5) | 0.18 | |
MVIC torque | PF | 30.7 (6.3) | 30.9 (6.7) | 0.98 | 46.6 (7.9) | 25.4 (3.9) | 0.09 |
DF | 11.4 (2.2) | 11.7 (2.9) | 0.94 | 17.1 (2.7) | 11.6 (1.5) | 0.16 | |
AROM | 54.2 (15.2) | 40.2 (8.3) | 0.55 | 48.4 (5.8) | 32.9 (3.7) | 0.09 | |
Vp | 189.4 (42.5) | 151.9 (34.0) | 0.65 | 160.7 (30.4) | 115.4 (15.9) | 0.27 | |