Optimal coil orientation for all target locations: The optimized electric field perpendicular to the CSF-GM boundary E⊥ (V m−1), just within the cortex, for all fourteen cortical target locations (Table 1). The cortical location index from Table 1 is shown in every right bottom corner. A positive value means directed inward and a negative means directed outward. The black dot indicates the location of the center of the TMS coil. The direction of the primary electric field directly under the coil center is indicated with the black arrow for the optimized coil orientation. The green arrow indicates direction of the primary electric field for the standard coil orientation.