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Table 3 Performance on the neuropsychological battery of the two groups (ADAPT-gr and CONST-gr) before (PRE) and after (POST) the cognitive rehabilitative intervention

From: Adaptive vs. non-adaptive cognitive training by means of a personalized App: a randomized trial in people with multiple sclerosis

Test CONST-gr ADAPT-gr p values
time PRE POST PRE POST  
SRT-LTS 32.14 (10.43)
(18.77–54.17)
38.33 (15.13)
(10.96–60.17)
24.59 (8.45)
(6.55–41.56)
39.79 (11.75)
(5.55–52.16)
NS
SRT-CLTR 19.98 (10.92)
(5.44–42.12)
23.50 (15.97)
(2.16–51.78)
15.80 (10.01)
(1.91–32.62)
31.08 (14.00)*
(3.91–53.24)
0.003
SPART 13.64 (4.91)
(3.94–23.56)
15.99 (3.70)
(10.94–24.62)
13.82 (4.58)
(8.31–23.78)
19.13 (5.46)
(10.31–28.15)
NS
SDMT 36.70 (9.54)
(21.24–50.53)
38.08 (9.09)
(19.24–51.53)
39.10 (11.60)
(22.24–61.38)
46.03 (11.52)*
(24.27–64.38)
0.0001
PASAT-3 33.43 (8.74)
(20.08–46.06)
32.99 (9.80)
(15.38–51.53)
28.11 (14.15)
(–1.02–43.68)
44.63 (13.60)*
(8.19–60.38)
0.0002
PASAT-2 22.17 (8.98)
(3.79–31.10)
24.12 (8.85)
(11.79–43.10)
18.10 (9.83)
(–0.67–35.45)
33.07 (11.12)*
(6.87–47.45)
0.0002
SRT-D 6.08 (2.54)
(2.48–10.88)
6.71 (3.19)
(1.48–12.88)
5.37 (1.88)
(1.87–7.88)
8.96 (2.18)*
(5.87–14.08)
0.0002
SPART-D 4.16 (2.48)
(–0.72–9.59)
5.30 (1.31)
(3.28–7.67)
4.56 (1.22)
(3.18–7.92)
6.15 (2.10)
(2.92–10.18)
NS
WLG 33.21 (10.88)
(7.88–64.88)
35.36 (12.73)
(15.88–50.88)
38.15 (5.96)
(23.88–49-12)
45.38 (7.37)*
(27.88–55-12)
0.0002
WCST 2.50 (1.74)
(0–5)
3.00 (1.57)
(0–5)
3.15 (1.46)
(0–5)
4.23 (1.36)
(2–6)
NS
  1. Abbreviations: SRT-LTS selective reminding test-long term storage, SRT-CLTR selective reminding test-consistent long-term retrieval, SPART 10/36 spatial recall test, SDMT symbol digit modalities test, PASAT-3/-2 paced auditory serial addition test, SRT-D selective reminding test-delayed, SPART-D 10/36 spatial recall test-delayed, WLG word list generation on semantic stimulus, WCST Wisconsin card sorting test, CONST-gr constant group, ADAPT-gr adaptive group
  2. Mean (SD, range) scores are reported for each test. Listed p values refer to post hoc comparison between PRE and POST results of ADAPT-gr where an effect of Group*Time was found