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Table 3 Performance on the neuropsychological battery of the two groups (ADAPT-gr and CONST-gr) before (PRE) and after (POST) the cognitive rehabilitative intervention

From: Adaptive vs. non-adaptive cognitive training by means of a personalized App: a randomized trial in people with multiple sclerosis

Test

CONST-gr

ADAPT-gr

p values

time

PRE

POST

PRE

POST

 

SRT-LTS

32.14 (10.43)

(18.77–54.17)

38.33 (15.13)

(10.96–60.17)

24.59 (8.45)

(6.55–41.56)

39.79 (11.75)

(5.55–52.16)

NS

SRT-CLTR

19.98 (10.92)

(5.44–42.12)

23.50 (15.97)

(2.16–51.78)

15.80 (10.01)

(1.91–32.62)

31.08 (14.00)*

(3.91–53.24)

0.003

SPART

13.64 (4.91)

(3.94–23.56)

15.99 (3.70)

(10.94–24.62)

13.82 (4.58)

(8.31–23.78)

19.13 (5.46)

(10.31–28.15)

NS

SDMT

36.70 (9.54)

(21.24–50.53)

38.08 (9.09)

(19.24–51.53)

39.10 (11.60)

(22.24–61.38)

46.03 (11.52)*

(24.27–64.38)

0.0001

PASAT-3

33.43 (8.74)

(20.08–46.06)

32.99 (9.80)

(15.38–51.53)

28.11 (14.15)

(–1.02–43.68)

44.63 (13.60)*

(8.19–60.38)

0.0002

PASAT-2

22.17 (8.98)

(3.79–31.10)

24.12 (8.85)

(11.79–43.10)

18.10 (9.83)

(–0.67–35.45)

33.07 (11.12)*

(6.87–47.45)

0.0002

SRT-D

6.08 (2.54)

(2.48–10.88)

6.71 (3.19)

(1.48–12.88)

5.37 (1.88)

(1.87–7.88)

8.96 (2.18)*

(5.87–14.08)

0.0002

SPART-D

4.16 (2.48)

(–0.72–9.59)

5.30 (1.31)

(3.28–7.67)

4.56 (1.22)

(3.18–7.92)

6.15 (2.10)

(2.92–10.18)

NS

WLG

33.21 (10.88)

(7.88–64.88)

35.36 (12.73)

(15.88–50.88)

38.15 (5.96)

(23.88–49-12)

45.38 (7.37)*

(27.88–55-12)

0.0002

WCST

2.50 (1.74)

(0–5)

3.00 (1.57)

(0–5)

3.15 (1.46)

(0–5)

4.23 (1.36)

(2–6)

NS

  1. Abbreviations: SRT-LTS selective reminding test-long term storage, SRT-CLTR selective reminding test-consistent long-term retrieval, SPART 10/36 spatial recall test, SDMT symbol digit modalities test, PASAT-3/-2 paced auditory serial addition test, SRT-D selective reminding test-delayed, SPART-D 10/36 spatial recall test-delayed, WLG word list generation on semantic stimulus, WCST Wisconsin card sorting test, CONST-gr constant group, ADAPT-gr adaptive group
  2. Mean (SD, range) scores are reported for each test. Listed p values refer to post hoc comparison between PRE and POST results of ADAPT-gr where an effect of Group*Time was found