Fig. 5

Stepping Impairments Change Over Time, Are Not Improved With BWSTT. a Healthy animals do not alter their stepping over 5 weeks of training as measured by relative error no greater than twice the difference between right and left limbs from week −1. One week following injury untrained injured animals are significantly different, with the less impaired left hindlimb spontaneously deviating further away as the weeks progress. This is interpreted as a development of compensatory techniques. b BWSTT improves right hindlimb stepping during the active training sessions (gray dots between weeks) but induces a deleterious after-effect when the BWS is removed for weekly assessments. This effect washes out the 2 weeks after the cessation of training. c BWSTT does not improve left hindlimb stepping, with little or no evidence of an after-effect, and no evidence of a washout following the cessation of testing. Levels of limb asymmetry for that week are found near each marker, with # indicating significance