Skip to main content

Table 1 Comparison of amperometric biosensors for measuring ATP concentration

From: An investigation into closed-loop treatment of neurological disorders based on sensing mitochondrial dysfunction

Title

Recognition Layer

Measured Quantity

Sensitivity (pA/μM)

Response Time

Electrode Size (μm)

Microelectrode Biosensor for Real-Time Measurement of ATP in Biological Tissue [153]

Glycerol kinase and glycerol-3-phosphate oxidase

H2O2

250

10s

25

ATP microelectrode biosensor for stable long-term in vitro monitoring from gastrointestinal tissue [199]

Glucose oxidase and hexokinase

H2O2

45.8

40–50s

50

Developmental aspects of amperometric ATP biosensors based on entrapped enzymes [200]

Pyrroloquinoline quinone-dependent glucose dehydrogenase and hexokinase

Various

290

50–200 s

25

Co-immobilization of glucose oxidase and hexokinase on silicate hybrid sol–gel membrane for glucose and ATP detections [201]

Glucose oxidase and hexokinase modified with silica hybrid sol-gel film

H2O2

10.8

15 s

3 × 103

Poly(benzoxazine) as immobilization matrix or miniaturized ATP and glucose biosensors [202]

Glucose oxidase and hexokinase with entrapment from a poly(benzoxazine) derivative

H2O2

48.5

–

25