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Table 1 Model parameters, assumptions and data sources

From: Economic benefits of microprocessor controlled prosthetic knees: a modeling study

Model parameter

Base case

Range

Data sources

Probability of falling per year

  

[26, 60]

 MPK

26.00%

22.20–32.00%

 NMPK

82.00%

75.00–87.50%

 Proportion of medical falls

10.40%

6.20–19.60%

[61,62,63]

 Proportion of fatal medical falls

7.00%

6.30–7.70%a

[64]

 Proportion of major injury falls

40.00%

32.60–40.00%

[65, 66]

 Proportion of minor injury falls

53.00%

53.00–60.50%

Average number of falls per faller per year

  

[26, 59]

 MPK

3.20

2.00–3.20

 NMPK

3.87

1.86–3.87

 Odds ratio of falling in year 4 vs. year 1

0.53

0.48–0.58a

[67]

 Medical cost per major injurious fall

$24,844.52

$16,978.61 - $31,707.24

[65, 66, 68]

 Medical cost per minor injurious fall

$1332.47

$620.69 - $6005.62

 Medical cost of fall-related death

$27,337.76

$27,337.76 - $29,578.20

[68, 69]

Caregiving expenses per person per year

  

[39, 70,71,72]

 MPK

$2754.29

$2478.86 - $3029.72a

 NMPK

$3477.60

$3129.84 - $3825.36a

Lost wages per person per year

  

 MPK

$1669.11

$1502.20 - $1836.02a

 NMPK

$2144.06

$1929.65 - $2358.47a

Transportation expenses per person per year

  

 MPK

$463.46

$417.11 - $509.81a

 NMPK

$300.36

$270.32 - $330.40a

Baseline prevalence of osteoarthritis (knee)

  

Medicare claims data 2011–2014

 K1/K2

16.30%

14.67–17.93%a

 K3/K4

19.10%

17.19–21.01%a

Probability of developing osteoarthritis per year

  

[34]; Expert opinion

 MPK

1.50%

1.35–1.65%a

 NMPK

2.21%

1.99 - 2.43%a

 Osteoarthritis-related medical cost per year

$6639.72

$996.41 - $14,682.92

[73]

 Osteoarthritis-related indirect cost per year

$1084.21

$606.89 - $1192.63

[74, 75]

Baseline mortality rate

  

Medicare claims data 2011–2014

 K1/K2

18.00%

16.20–19.80%a

 K3/K4

9.31%

8.38–10.24%a

Device acquisition cost in 10 years

  

2016 Medicare fee schedule; Medicare claims data 2011–2014; Expert opinion

 MPK (plus 1 replacement)

$56,000.00

$44,750.00 - $58,118.00

 NMPK (plus 2 replacements)

$16,500.00

$7785.00 - $22,101.00

Device repair cost per year

  

 MPK

$192.23

$173.01 - $211.45a

 NMPK

$135.95

$122.36 - $149.55a

Physical therapy cost in year 1

  

 MPK

$1986.68

$1788.01 - $2185.35a

 NMPK

$1648.62

$1483.76 - $1813.48a

Physical therapy cost in year 2

  

 MPK

$1621.68

$1459.51 - $1783.85a

 NMPK

$1347.47

$1212.72 - $1482.21a

Health utilities

  

[37,38,39,40]

 MPK

0.82

0.75–0.83

 NMPK

0.66

0.60–0.92

Discount rate

3.00%

2.00–5.00%

[76]

  1. MPK microprocessor-controlled knees, NMPK non-microprocessor controlled knees. K1-K4: Medicare Functional Classification Level 1 to 4, respectively
  2. aThere are no range values directly from the literature; in the sensitivity analyses, they were derived through varying the base case value up and down by 10%. The design of the studies comparing the effectiveness of MPK to NMPK: Prospective cohort study [26, 39, 59, 60]; Retrospective cohort study [37, 40]; Cross-sectional study [38])