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Table 6 Comparison of the proposed instrument’s AFE with state-of-the-art ASICs for biopotential signal acquisition (note that, as anticipated, a tradeoff exists between ultra-low power consumption (state-of-the-art ASICs) and superior noise performance (proposed instrument’s AFE))

From: A high-performance 8 nV/√Hz 8-channel wearable and wireless system for real-time monitoring of bioelectrical signals

Parameters [46] [47] [48] [49] [50] This work
Supply 0.2/0.8 V 1 V 1.8 V 1.8 V 3 V ±5 V
Technology 0.18 μm CMOS 0.18 μm CMOS 0.8 μm CMOS 0.18 μm CMOS 0.5 μm CMOS
Voltage gain 776 V/V 100 V/V 100 V/V 3–100 V/V 10 V/V 1000 V/V
Input impedance ≈ 100 MΩ >  700 MΩ >  7.5 MΩ >  2 GΩ >  100 MΩ 200 GΩ
Input referred noise 0.94 μV rms
(0.5–670 Hz)
1.3 μV rms
(0.5–100 Hz)
0.95 μV rms
(0.05–100 Hz)
0.8 μV rms
(0.5–100 Hz)
0.6 μV rms
(0.5–100 Hz)
85 nV rms
(0.5–100 Hz)
DC tolerance Rail-to-rail ±50 mV Rail-to-rail ±50 mV ±85 mV
CMRR 85 dB 60 dB 100 dB 82 dB 120 dB 134 dB
Current ≈ 1 μA 3.5 μA 1.1 μA 11 μA 11.1 μA ≈ 2.5 mA