Quantitative clinical assessment of motor function during and following LSVT-BIG® therapy

Table 3 List of standard clinical measures and ACC sensor-derived measures with their respective statistical results calculated for each task. Numbers listed in bold font indicate significant p-values for one-way RANOVA (α = 0.05) and multiple comparisons with CON_Health at stages Pre1, S15 and Post3 (α = 0.017) using student’s two-sample T-test

Task	Feature		Unit	RANOVA	Multiple Comparison w/ CON_PD
Task	Feature		Unit	RANOVA	*Pre1*	*S15*	*Post3*
i10MW	Measured Time		s	< 0.001	0.545	0.023	0.029
	Gait Times	Step	s	< 0.001	0.584	0.125	0.061
		Stride	s	< 0.001	0.525	0.143	0.070
		Swing	s	< 0.001	0.292	0.395	0.153
		Stance	s	0.037	0.787	0.091	0.095
	Gait Asymmetry		a.u.	0.932	0.973	0.896	0.728
	Gait Regularity		a.u.	0.317	0.640	0.639	0.179
	Step Time Var		s	0.567	0.730	0.313	0.303
iTUG	Measured Time		s	< 0.001	0.117	0.355	0.197
	Step Count		#	0.011	0.066	0.465	0.163
	Time to First Step		s	0.501	0.582	0.376	0.227
	Gait Times	Step	s	< 0.001	0.926	0.059	0.013
		Stride	s	< 0.001	0.849	0.066	0.011
		Swing	s	< 0.001	0.689	0.120	0.017
		Stance	s	0.004	0.515	0.163	0.165
iSTS	STS Count		#	< 0.001	0.006	0.372	0.465
	STS Times	Total	s	0.001	0.025	0.946	0.193
		Sit-to-Stand	s	< 0.001	0.014	0.823	0.770
		Stance	s	0.011	0.058	0.814	0.244
		Stand-to-Sit	s	< 0.001	0.029	0.931	0.051
		Sit	s	0.046	0.107	0.343	0.617
	Average Jerk		m/s³	0.032	0.321	0.800	0.226
	STS Variance		a.u	0.092	0.073	0.936	0.253
QS	Total Displacement		mm	0.509	0.063	0.081	0.081
	Standard Deviation	AP	m/s²	0.324	0.129	0.142	0.088
	Standard Deviation	ML	m/s²	0.587	0.112	0.204	0.197
	Range	AP	m/s²	0.315	0.163	0.113	0.108
	Range	ML	m/s²	0.704	0.451	0.441	0.365
	Normal Path Length	AP	m/s	0.117	0.220	0.026	0.003
	Jerk		m²/s⁵	0.838	0.296	0.245	0.338
FT	FT Count		#	0.424	0.819	0.962	0.887
	Intertap Interval		s	0.430	0.761	0.497	0.857
	Kurtosis		a.u.	0.492	0.098	0.226	0.284
	Skewness		a.u.	0.538	0.159	0.881	0.495
	10s/30s Count		a.u.	0.379	0.957	0.445	0.324

ISSN: 1743-0003