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Table 3 List of standard clinical measures and ACC sensor-derived measures with their respective statistical results calculated for each task. Numbers listed in bold font indicate significant p-values for one-way RANOVA (α = 0.05) and multiple comparisons with CONHealth at stages Pre1, S15 and Post3 (α = 0.017) using student’s two-sample T-test

From: Quantitative clinical assessment of motor function during and following LSVT-BIG® therapy

Task Feature Unit RANOVA Multiple Comparison w/ CONPD
Pre1 S15 Post3
i10MW Measured Time   s <  0.001 0.545 0.023 0.029
Gait Times Step s <  0.001 0.584 0.125 0.061
Stride s < 0.001 0.525 0.143 0.070
Swing s < 0.001 0.292 0.395 0.153
Stance s 0.037 0.787 0.091 0.095
Gait Asymmetry   a.u. 0.932 0.973 0.896 0.728
Gait Regularity   a.u. 0.317 0.640 0.639 0.179
Step Time Var   s 0.567 0.730 0.313 0.303
iTUG Measured Time   s < 0.001 0.117 0.355 0.197
Step Count   # 0.011 0.066 0.465 0.163
Time to First Step   s 0.501 0.582 0.376 0.227
Gait Times Step s < 0.001 0.926 0.059 0.013
Stride s < 0.001 0.849 0.066 0.011
Swing s < 0.001 0.689 0.120 0.017
Stance s 0.004 0.515 0.163 0.165
iSTS STS Count   # < 0.001 0.006 0.372 0.465
STS Times Total s 0.001 0.025 0.946 0.193
Sit-to-Stand s < 0.001 0.014 0.823 0.770
Stance s 0.011 0.058 0.814 0.244
Stand-to-Sit s < 0.001 0.029 0.931 0.051
Sit s 0.046 0.107 0.343 0.617
Average Jerk   m/s3 0.032 0.321 0.800 0.226
STS Variance   a.u 0.092 0.073 0.936 0.253
QS Total Displacement   mm 0.509 0.063 0.081 0.081
Standard Deviation AP m/s2 0.324 0.129 0.142 0.088
ML m/s2 0.587 0.112 0.204 0.197
Range AP m/s2 0.315 0.163 0.113 0.108
ML m/s2 0.704 0.451 0.441 0.365
Normal Path Length AP m/s 0.117 0.220 0.026 0.003
Jerk   m2/s5 0.838 0.296 0.245 0.338
FT FT Count   # 0.424 0.819 0.962 0.887
Intertap Interval   s 0.430 0.761 0.497 0.857
Kurtosis   a.u. 0.492 0.098 0.226 0.284
Skewness   a.u. 0.538 0.159 0.881 0.495
10s/30s Count   a.u. 0.379 0.957 0.445 0.324