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Table 1 Studies investigating initiation and acceleration of walking listed by increasing walking speed

From: Brain activity during real-time walking and with walking interventions after stroke: a systematic review

Authors

Device

[ROI]; method of placing channels

Walking time analyzed, task and speed: m/s (SD)

Results

(Mihara et al., 2007) [39]

fNIRS

[PFC, SMA, SMC];

anatomically guided from 2 representative subjects

4–10 s post-treadmill start, Treadmill, fast, comfortable pace:

Stroke: 0.33 (0.22)

Healthy: 0.97 (SD not provided)

1. Increased PFC, SMA, and SMC activation

2. Greater increase in right PFC and bilateral SMA for the stroke compared to healthy group

3. No between group differences for SMC

(Hawkins et al., 2018) [36]

fNIRS

[PFC];

placed high and lateral on the forehead

7–37 s after start command, Overground, preferred speed:

Stroke: 0.51 (0.27)

Older adults: 1.07 (0.16)

Young adults: 1.28 (0.18)

1. Increased PFC activity

2. No difference in PFC activity between hemispheres, side of stroke, or gender

2. Greater increase in PFC activity compared to young adults, but not compared to older adults

(Sburlea et al., 2015) [29]

EEG

[Whole head];

10/10 system

−1.5–0 s prior to start,

Overground, comfortable pace: exact pace not specified

1. Activation at SMA and M1 500 ms prior to walking onset

2. More widespread activation in stroke group compared to healthy young adults (from Sburlea et al. [29]). Though no statistical comparisons made

  1. All results are reported in comparison to baseline activation (typically standing prior to walking)
  2. ROI  region of interest, PFC  prefrontal cortex, SMA supplementary motor area, SMC  sensorimotor cortex, M1  primary motor cortex, fNIRS  functional near-infrared spectroscopy, EEG  electroencephalography
  3. *Sburlea et al. [46] was included with their 2015 publication as they used the same data set in both studies