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Table 2 Sociodemographic and clinical characteristics of the subjects with stroke

From: Transcranial direct current stimulation combined with robotic therapy for upper and lower limb function after stroke: a systematic review and meta-analysis of randomized control trials

Author

(year)

Participants (n)

[enrolled]

Gender

M/F

Age

Mean (SD)

Classification

Type

I/H

Pathology characteristics

Duration

Mean (SD)

      

Affected side

Right/left

Location of lesion

C/SC

Geroin C. et al. (2011)29

n = 30

tDCS (n = 10)

Sham (n = 10)

Control (n = 10)

tDCS: 8/2

Sham: 6/4

Control: 9/1

tDCS: 63.6 (6.7)

Sham: 63.3 (6.4)

Control: 61.1 (6.3)

Chronic

tDCS: 4/3

Sham: 5/2

Control: 3/4

tDCS:25.7 (6.0)

Sham: 26.7 (5.1)

Control: 26.9 (5.8)

months

Hesse S. et al. (2011)2830

n = 96

Anodal tDCS (n = 32) Cathodal tDCS (n = 32)

Sham (n = 32)

Anodal tDCS: 20/12

Cathodal tDCS: 18/14

Sham: 21/11

Anodal tDCS: 63.9 (19.5)

Cathodal tDCS: 65.4 (8.6)

Sham: 65.6 (10.3)

Subacute

Anodal tDCS: 32/0

Cathodal tDCS: 32/0

Sham: 32/0

Anodal tDCS: 14/18

Cathodal tDCS: 15/17

Sham: 16/16

Anodal tDCS: 25/7

Cathodal tDCS: 24/8

Sham: 26/6

Anodal tDCS: 3.4 ± 1.8

Cathodal tDCS: 3.8 ± 1.4

Sham: 3.8 ± 1.5

weeks

Danz M. et al. (2013)2931

n = 8

tDCS (n = 4)

Sham (n = 4)

tDCS: 3/1

Sham: 1/3

tDCS: 64.75 (14.86)

Sham: 70.75 (11.14)

Chronic

 > 12 months

tDCS: 2/2

Sham: 4/0

tDCS: 0/4

Sham: 0/4

tDCS: 4.78 (4.6)

Sham: 3.22 (2.73)

years

Triccas T. et al. (2015)3032

n = 23

tDCS (n = 12)

Sham (n = 11)

tDCS: 7/5

Sham: 7/4

tDCS: 62.5 (14.3)

Sham: 64.3 (9.94)

Subacute and chronic

 > 2 months

tDCS: 9/3

Sham: 9/2

tDCS: 11/2

Sham: 11/0

tDCS: 3/8

Sham:4/6

19.6 (25.7)

months

Straudi. S et al

(2016)3133

n = 23

tDCS (n = 12)

Sham (n = 11)

tDCS: 5/7

Sham: 7/4

tDCS: 52.7 (16.0)

Sham: 64.3 (9.7)

Subacute and chronic

tDCS: 10/2

Sham: 9/2

tDCS: 3/9

Sham: 5/6

tDCS: 9/3

Sham: 5/6

tDSC: 40.7 (35.1)

Sham: 78.2 (61.9)

weeks

Seo HG et al

(2017)3234

n = 21

tDCS (n = 11)

Sham (n = 10)

Sham: 7/3

tDCS: 9/2

Sham: 62.9 ± 8.9

tDCS: 61.1 ± 8.9

Chronic

Sham: 7/3

tDCS: 9/2

Sham: 8/2

tDCS: 5/6

Sham: 152.5 ± 122.8

tDCS: 75.5 ± 83.4

months

Mazzoleni S et al

(2017)3335

n = 24

tDCS (n = 12)

Sham (n = 12)

Sham: 6/6

tDCS: 1/11

Sham: 75.25 ± 8.01

tDCS: 70.00 ± 12.80

Subacute

Sham: 11/1

tDCS: 7/5

Sham: 6/6

tDCS: 6/6

Sham: 24.17 ± 14.02 tDCS:26.58 ± 11.86

days

Dehem et al

(2018)3436

n = 21

Crossover

15/6

Total: 60.5 (9.5)

Chronic

Total: 15/6

Total: 11/10

14/7

Total: 38.6 (57.0)

months

Edwards et al

(2019)3537

n = 82

Robot + tDCS (n = 41)

Robot + sham (n = 41)

50/32

67.8

Chronic

Ischaemic

Right (82)

1317 days

3.6 years

Mazzoleni et al

(2019)3638

n = 40

tDCS (n = 20)

Sham (n = 20)

Sham: 7/12

tDCS: 8/12

Sham: 68.74 ± 15.83

tDCS: 67.50 ± 16.30

Subacute Stroke

Sham: 16/3

tDCS: 13/7

Sham: 11/8

tDCS: 11/9

25 ± 7 days

  1. Male (M); Female (F); Standard Deviation (SD); Ischaemic (I); Haemorrhagic (H); Cortical (C); Subcortical (SC); Group (G); Transcranial direct current stimulation (tDCS)