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Table 1 Summary of 34 new cases of peripheral nerve injury after severe COVID-19

From: The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor

#

Age/Sex

Site

Risk Factors

PNI sites (laterality)

Diagnostics

Clinical presentation(s)

1

60s/M

SRAlab

DM, Obese

Sciatic (left), Fibular (right)

EDX (axonal)

Bilateral foot drop; Left worse than right

2

50s/M

SRAlab

DM

Ulnar (left)

EDX (demyelin.)

Left hand weakness

3

40s/F

SRAlab

Obese

Cervical radiculopathy (left)

EDX (axonal)

Neck pain; Left shoulder and elbow flexion weakness

4

60s/M

SRAlab

DM

Femoral (left), Obturator (left), Spinal accessory (right)

EDX (axonal), MRI (pelvis)

Left thigh pain and paresthesia; Left knee extension weakness; Right sided neck and shoulder pain

5

70s/M

SRAlab

None

Sciatic (right), Fibular (left)

EDX (axonal)

Bilateral foot drop; Right worse than left

6

30s/M

SRAlab

Obese

Sciatic (right), Fibular (left), Phrenic (right)

EDX (axonal), US (phrenic)

Bilateral foot drop; Right worse than left; Shortness of breath on exertion

7

40s/M

SRAlab

None

Phrenic (right)

US (phrenic)

Shortness of breath on exertion

8

60s/M

SRAlab

HIV

Radial (right), Ulnar (right), Median (right), Sciatic (right), Ulnar (left), Median (left)

EDX (axonal; but demyelin. median)

Diffuse, but asymmetric weakness and sensory disturbance

9

60s/M

SRAlab

Obese

Brachial plexopathy (right), Ulnar (right), Median (right), Phrenic (right)

EDX (axonal; but demyelin. ulnar), US (phrenic)

Diffuse right arm weakness and sensory disturbance; Shortness of breath

10

60s/M

SRAlab

None

Fibular (right)

EDX (axonal)

Right foot drop; Paresthesia in right foot

11

70s/M

SRAlab

CKD

Femoral (right), Obturator (right), Fibular (right)

EDX (axonal), MRI (pelvis)

Right knee buckling and weakness; Right foot drop

12

50s/M

SRAlab

DM

Cervical radiculopathy (left), Ulnar (left), Phrenic (right)

EDX (axonal), MRI (neck/shoulder), US (phrenic)

Left shoulder and elbow flexion weakness; Left hand weakness; Shortness of breath on exertion

13

60s/M

SRAlab

DM

Sciatic (right), Phrenic (right)

EDX (axonal), US (phrenic)

Right foot drop; Shortness of breath on exertion

14

30s/M

SRAlab

Obesity

Sciatic (left)

EDX (axonal)

Left foot drop

15

40s/M

SRAlab

None

Fibular (left), Fibular (right)

EDX (axonal)

Bilateral foot drop

16

60s/M

SRAlab

None

Ulnar (right), Radial (right), Median (right), Ulnar (left), Radial (left)

EDX (axonal)

Bilateral forearm and hand weakness in extension and flexion; Worse on right

17

70s/F

SRAlab

DM

Sciatic (left)

EDX (axonal)

Left foot drop

18

70s/M

SRAlab

DM, CKD

Fibular (left)

EDX (axonal)

Left foot drop

19

50s/M

SRAlab

Obese

Sciatic (right), Fibular (left)

EDX (axonal)

Bilateral foot drop; Worse on right side

20

40s/M

SRAlab

DM, Obese

Fibular (right), Fibular (left)

EDX (axonal)

Bilateral foot drop

21

70s/M

SRAlab

None

Ulnar (left), Lateral femoral cutaneous (left)

EDX (axonal, but clinical LFCN)

Left hand weakness; Painful paresthesia in left anterolateral thigh

22

50s/M

SRAlab

None

Ulnar (left)

EDX (axonal)

Left hand weakness

23

50s/M

NMH

DM, Obese

Radial (right)

None (clinical)

Right wrist drop and forearm pain

24

30s/F

NMH

DM, Obese

Sciatic (left)

EDX (axonal)

Left foot drop

25

30s/M

NMH

Obese

Ulnar (left)

EDX (axonal)

Left hand weakness

26

40s/M

NMH

Obese

Radial (left)

EDX (axonal)

Left wrist drop

27

20s/M

NMH

DM, Obese

Ulnar (left)

EDX (axonal)

Left hand weakness

28

20s/M

NMH

Obese

Brachial plexopathy (left), Radial (right)

EDX (axonal)

Left shoulder and elbow flexion weakness; Right wrist drop

29

60s/M

NMH

Obese

Brachial plexopathy (left), Ulnar (left), Sciatic (left), Fibular (right)

EDX (axonal; but demyelin. ulnar)

Left shoulder and elbow flexion weakness; Left hand weakness; Bilateral foot drop

30

30s/F

MRH

DM, Obese

Fibular (right), Fibular (left)

EDX (axonal)

Bilateral foot drop

31

60s/M

MRH

None

Fibular (right)

EDX (axonal)

Right foot drop

32

60s/M

MRH

DM, Obese

Brachial plexopathy (right)

EDX (axonal)

Diffuse right arm weakness and numbness

33

70s/M

MRH

DM, Obese

Fibular (right), Fibular (left)

None (clinical)

Bilateral foot drop

34

30s/M

MRH

DM, Obese

Median (right), Median (left)

EDX (axonal)

Bilateral hand weakness and paresthesia

  1. PNI, peripheral nerve injury; SRAlab, Shirley Ryan AbilityLab (rehabilitation hospital); NMH, Northwestern Memorial Hospital; MJH, Marianjoy Rehabilitation Hospital; DM, diabetes mellitus; HIV, human immunodeficiency virus; CKD, chronic kidney disease; EDX, electrodiagnostics; MRI, magnetic resonance imaging; US, ultrasound; demyelin., demyelinating; LFCN, lateral femoral cutaneous nerve. In accordance with journal policy, patient age is expressed according to their decade of life