Inclusion Criteria | Exclusion Criteria |
---|---|
∙ 18–70 years of age ∙ Traumatic and non-traumatic SCI ∙ AIS grade A to–D with sufficient arm strength to support body weight on a walking frame ∙ Currently receiving treatment as an inpatient or outpatient at one of the investigational sites ∙ Ability to give informed consent | ∙ WISCI II [19] without exoskeleton of > 16 ∙ History of lower-limb fragility fractures in the last 2 years ∙ 5 or more risk factors present for fragility fractures as stated by Craven et al. [18] ∙ Deterioration > 3 points of the total ISNCSCI motor score within the last 4 weeks ∙ Spinal instability ∙ Modified Ashworth scale [20]  > 3 in lower limbs ∙ Unable to tolerate 30 min standing without clinical symptoms of orthostatic hypotension ∙ Unable to perform a sit-to-stand transfer or stand in the device with assistance ∙ Psychological or cognitive issues that do not allow the participant to follow the study procedures ∙ Known pregnancy or breastfeeding ∙ Any neurological condition other than SCI ∙ Medically unstable (Unstable CVS, hemodynamic instability, untreated hypertension (SBP > 140, DBP > 90 mmHg), unresolved DVT, uncontrolled AD) ∙ Severe comorbidities (any condition that a physician considers to not be appropriate to complete participation in the study) ∙ Ongoing skin issues (Grade I or higher on the European Pressure Ulcer Advisory Panel (EPUAP) scale [23] on areas that will be in contact with the exoskeleton) ∙ Height, width, weight or other anatomical constraints (such as leg length differences) incompatible with the device ∙ Insufficient ROM for device preventing a participant to achieve a normal gait pattern or to complete a sit-to-stand/stand-to-sit transition (hip joint: insufficient ROM for step length, knee joint: insufficient ROM for standing, ankle: insufficient ROM to reach neutral position) |