Median (range) | |
---|---|
Age (years) | 66 (59–69) |
Height (m) | 1.76 (1.66–1.90) |
Weight (kg) | 77 (60–95) |
Duration of disease (years) | 18 (10–22) |
Duration of DBS treatment (months) | 37 (15–70) |
DBS parameter settings1 | |
Right (amplitude: V, pulsewidth: μs, frequency; Hz) | 3.3 (2.5–4.3), 60 (60–90), 145 (100–185) |
Left (amplitude: V, pulsewidth: μs, frequency; Hz) | 3.4 (2.2–4.3), 60 (60–90), 130 (100–185) |
Localization of the contacts with negative polarity | |
Right | 11.7 (10.4–13.1) mm lateral to the midsagittal plane through the intercommissural line (IC), 3.4 (3.0–4.0)mm posterior to the midpoint of IC and 2.1 (1.0–5.6)mm inferior to IC. |
Left | 11.4 (9.6–13.0) mm lateral, 3.5 (3.3–5.2) mm posterior, and 2.6 (1.2–4.2) mm inferior to IC. The median length of IC was 24.8 (23.5–25.6) mm |
L-dopa equivalents (mg/day)2 | 416 (242–989) |
Physical Activity Scale for the Elderly (PASE)3 | 112 (75–187) |
UPDRS part III4 total score | DBS OFF: 41.0 (35.0–83.5), DBS ON: 21.5 (11.0–30.5) |
n | |
Occupation | 10 retired (6 due to age, 4 due to disease) |
Comorbidity | 2 (1 patient had lumbar degenerative changes, 1 had hypertonia and a previous heart infarct) |
Postural hypotension5 | None |
Prior surgery related to Parkinson's disease6 | 2 (1 pallidotomy, 1 thalamotomy + earlier DBS surgery) |
Pain symptoms | 6 (2 hip pain, 2 back pain, 2 shoulder pain) |
Assistive device (walking indoors) | None |
Assistive device (walking outdoors) | 1 (cane) |
Falls within the past 6 months7 | 7 patients reported falls (range 1–15 falls), whereof 5 patients reported at least 2 falls |
3 patients reported no falls: 1 experienced near falls every week, and 2 every month (whereof one of the two had fractured twice due to falls, but the last incidence was a year before the study) |