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Table 2 Baseline comparisons between participant characteristics for early responders and non-early responders

From: Time course of changes in motor-cognitive exergame performances during task-specific training in patients with dementia: identification and predictors of early training response

Variable

ERs (n = 31)

NERs (n = 21)

p-value

Age, yearsa

83.5 ± 6.5 [65–93]

82.3 ± 6.0 [70–94]

.514

Femalesb

23 (74.2)

14 (66.7)

.557

Mini-Mental State Examination, scorea

21.4 ± 2.8 [17–26]

23.0 ± 2.4 [17–26]

.039

Diagnosesa

7.5 ± 3.4 [1–17]

7.5 ± 4.1 [1–17]

.994

Medicationsa

7.3 ± 3.3 [0–13]

8.1 ± 3.6 [0–14]

.419

Timed Up and Go, sc

14.8 [9.8–52.7]

13.9 [6.5–51.2]

.714

Performance Oriented Mobility Assessment, scorea

22.2 ± 4.0 [12–28]

23.1 ± 3.9 [15–28]

.405

5-chair stand test, s

14.8 ± 7.6 [6.8–39.1]

13.5 ± 5.1 [7.2–29.4]

.522

Geriatric Depression Scale, scorec

2 [0–9]

2 [0–8]

.799

Falls Efficacy Scale-International, scorec

8 [7–13]

8 [7–19]

.826

Fall in the previous year

13 (41.9)

8 (38.1)

.782

CERAD scoresa

 Total score

70.7 ± 8.7 [54–87]

77.2 ± 12.0 [54–87]

.026

 Verbal fluency

9.7 ± 3.7 [3–17]

11.3 ± 3.5 [4–18]

.124

 Boston Naming Test

9.9 ± 2.7 [5–15]

11.0 ± 2.4 [5–14]

.150

 Word list memory

10.5 ± 3.1 [4–16]

11.2 ± 3.8 [5–16]

.484

 Word list recall

2.1 ± 1.8 [0–6]

2.0 ± 1.8 [0–5]

.900

 Word list recognition

6.1 ± 2.7 [1–10]

7.1 ± 2.4 [2–10]

.172

 Constructional praxis

7.0 ± 2.3 [2–11]

8.7 ± 1.8 [6–11]

.006

 Constructional recall

1.7 ± 2.1 [0–7]

2.3 ± 2.2 [0–6]

.337

 Phonemic fluency

6.8 ± 3.1 [0–15]

6.7 ± 4.0 [0–16]

.900

TMT-NAI, sc

114 [35–300]

57 [32–300]

.001

DST-NAI scorea

8.6 ± 1.3 [6–11]

9.2 ± 1.0 [7–11]

.098

Dual-task performance (DTCcombined), %a

−36.1 ± 22.3 [− 82.5- -0.4]

−24.0 ± 16.8 [− 54.0- -0.2]

.040

Baseline Physiomat® performance, s

 FTBTc

37.6 [18.5–121.1]

21.2 [17.1–31.5]

< .001

 PTMT-L1c,d

15.6 [5.8–136.1]

8.2 [5.3–19.8]

< .001

 PTMT-L2c,e

24.7 [10.3–57.3]

15.8 [10.5–21.5]

< .001

 PTMT-L3a,f

34.7 ± 12.4 [21.6–64.5]

22.4 ± 6.4 [13.2–37.6]

< .001

 PTMT-L4a,g

61.5 ± 16.2 [37.8–91.4]

44.9 ± 12.0 [31.6–67.5]

.007

 PTMT-L5a,h

66.4 ± 8.7 [52.6–75.1]

53.7 ± 10.7 [39.1–76.9]

.036

Training adherence at TS7a

81.1 ± 20.3 [42.9–100]

76.7 ± 20.9 [33.3–100]

.451

  1. Data are presented as mean ± SD [range], n (%), or median [range]. ERs, early responders; NERs, non-early responders; CERAD, Consortium to Establish a Registry for Alzheimer’s Disease, TMT-NAI, Trail Making Test from the Nuremberg Age Inventory; DST-NAI, Digit-Span Test from the Nuremberg Age Inventory; DTCcombined, combined dual-task costs (i.e. [motor + cognitive dual-tasks costs]/2); FTBT, Physiomat®-Follow The Ball Task; PTMT, Physiomat®-Trail Making Task; L1–5, level 1–5. P-values for at-tests, bχ2 test, and cMann-Whitney U-tests. P-values in bold indicate statistical significance (p ≤ .05). Comparison between dn = 30 ERs vs. n = 20 NERs, en = 27 ERs vs. n = 18 NERs, fn = 21 ERs vs. n = 18 NERs; gn = 12 ERs vs. n = 13 NERs, hn = 5 ERs vs. n = 9 NERs