Fig. 1
From: Control of cortical oscillatory frequency by a closed-loop system
Closed-loop system. At the bottom of the figure is a photograph of four cortical slices in the recording chamber. In a counterclockwise direction, the loop proceeds from recording to stimulation. To the right, a sample of the local field potential (LFP) signal recorded from layer 5 is amplified, digitalized and sent to the PC via USB. At the top, the PC performs the online analysis for Up-state recognition and slow oscillation (SO) computation. To the left, the custom-made stimulator is controlled by the PC via Bluetooth. The stimulator injects DC current (i) into the slices by creating an adequate potential difference (ΔV) between the stimulation electrodes