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Table 3 Clinical measures and stimulation parameters for high-frequency stimulation (HFS) and low-frequency stimulation (LFS) during self-selected comfortable and quick walking speeds

From: Low-frequency STN-DBS provides acute gait improvements in Parkinson’s disease: a double-blinded randomised cross-over feasibility trial

  HFS LFS Sig
  Mean (SD) Mean (SD)  
Clinical measures    
MDS-UPDRS III 32.7 (10.7) 30.9 (9.8) 0.675
Retropulsion test 1.4 (1.3) 1.1 (1.2) 0.623
Comfortable 6 m walk test (s) 5.3 (0.9) 5.4 (1.2) 0.809
Quick 6 m walk test (s) 4.1 (0.8) 4.1 (0.9) 0.837
Timed up and go (s) 18.9 (5.7) 17.4 (3.4) 0.513
Stimulation parameters    
Frequency (Hz) 126.1 (12.3) 60.0 (0.0)  < 0.001
Amplitude (V) 3.3 (0.7) 4.7 (1.1)  < 0.001
Pulse width (μsec) 62.1 (5.5) 62.1 (5.5) 1.000
  1. Data represent the mean (± 1 standard deviation)
  2. MDS-UPDRS III motor subscale of the Movement Disorders Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale, s seconds