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Table 4 Summary of efficacy of BWSTT exoskeleton-assisted gait training

From: Effect of exoskeleton-assisted Body Weight-Supported Treadmill Training on gait function for patients with chronic stroke: a scoping review

4.1 BSWTT-RAGT vs BSWTT-TAGT

Author

Hornby et al. [35]

Belas Dos Santos et al. [36]

Lewek et al. [38]

Westlake et al. [39]

Additional treatment provided

N/A

Conventional PT

N/A

N/A

Results in BSWTT-RAGT groups (pre, post change, p < 0.05)

Body function/structure level

SSV + 0.07, d = 0.29

FV + 0.06, d = 0.19

SARA − 3.5, d = 0.49

BBS + 5.8, d = 0.31

TUG − 0:19 s, d = 0.64

No change

FMLE + 2.6, d = 0.56,

BBS + 1.4, d = 0.2

SS + 0.01 m/s, d = 0.29

FV + 0.09 m/s, d = 0.15

SLR (abs) − 0.16, d = 0.31

Activity level

FIM + 4.6, d = 0.34

Results between groups (p < 0.05)

BWSTT-TAGT group showed greater improvements in SSV + 0.06 m/s, d = 0.65, FV + 0.07 m/s, d = 0.69, Single limb stance time at FV: + 2.4 ± 3.7%, d = 0.91

No significant difference

No significant difference

No significant difference

4.2 BSWTT-RAGT vs BSWTT-RAGT with combination therapy

Author

Danzl et al. [40]

Bae et al. [41]

Additional treatment provided

tDCS for experimental group

FES for experimental group

Conventional PT

Results in BSWTT-RAGT groups (pre, post change, p < 0.05)

Body function/structure level

10MWT + improved

MAS + 1.92, d = 0.27

TUG − 5.63 s, d = 0.38

BBS + 3.43, d = 0.41

Gait speed + 0.007 m/s, d = 0.47

Step length + 0.05, d = 0.43

Stride length + 0.33, d = 0.33

Maximal Knee flexion + 18.747 d = 1.07

Maximal Knee flexion + 6.904 d = 0.58

Activity level

FAC + improved

SIS-16 + improved

Results between groups (p < 0.05)

BSWTT-RAGT with active tDCS group showed greater improvement than the sham group in 10MWT, FAC, and SIS-16 measures except BBS

BSWTT-RAGT with FES group showed a significantly greater in Maximal Knee flexion + 8.97, d = 0.56

4.3 BSWTT-RAGT vs BWSTT

Author

Ogino et al. [42]

Ogino et al. [43]

Additional treatment provided

N/A

N/A

Results in BSWTT-RAGT groups (pre, post change, p < 0.05)

Body function/structure level

GRC scale (change of gait)

 + improved

10MWT + 0.09 m/s

Activity level

Results between groups (p < 0.05)

No significant difference

BSWTT-RAGT group were significantly improved in TUG (r = 0.57), 6-min walk (r = 0.51) and score of general health in SF-8 (r = 0.49)

4.4 Other

Author

Assist unaffected limb vs affected limb

HRR vs RPE guided BSWTT-RAGT

BSWTT-RAGT vs Conventional PT

Seo et al. [37]

Bae et al. [44]

Erbil et al. [45]

Additional treatment provided

N/A

N/A

Conventional PT

BoNT-A

Results in BSWTT-RAGT groups (pre, post change, p < 0.05)

Body function/structure level

Assist US:

FMLE + 3.2, d = 1.18

MI + 11.7, d = 2.32

Step length asymmetry ratio -0.2, d = 2.0

Hip maximal extension moment (US) -0.5, d = 1.79

Assist AS:

FMLE + 2.7, d = 1.29

Ankle maximal dorsiflexion angle (US) -8.9, d = 3.26

HRR guided:

FMLE + 3.67, d = 0.23, 10MWT + 0.22 m/s, d = 0.80, WS + 0.20 m/s, d = 1.53

And Improved in Stride length, Cadence, Single and Double support rate, Swing time, Stance time, Step length, and Symmetrical index

RPE guided:

FMLE + 2.20, d = 0.63, 10MWT + 0.13 m/s, d = 0.41, WS + 0.14 m/s, d = 0.14

And Improved in Stride length, Cadence, Single support rate Single and Double support rate, Swing time, Stance time, Step length, Symmetrical index

MAS − 1.5, d = 2.94

Tardieu Scale (spasticity grade) − 0.2, d = 0.44

BBS + 2.7, d = 0.29

TUG + 5.7, d = 0.66

Activity level

Assist US: FAC + 0.7, d = 2.33

RVGA + 5.3, d = 1.0

Results between groups (p < 0.05)

No significant difference

HRR-guided group showed significantly improved in compared to RPE-guided group in FMLE, 10MWT, WS, Stride length, Cadence, Single support rate, Single and Double support rate, Swing time, Symmetrical index

BSWTT-RAGT group is significantly higher in TUG, BBS, and RVGA

  1. Each study was categorised according to the characteristics of the comparison group under investigation. The results of BWSTT-RAGT intervention groups in pre-post change (p < 0.05) and results compared to the control group are shown. Descriptive values are presented as the mean change and d describes effect size. Results were categorised as Body function/structure level and Activity level [55, 56]. RAGT Robot-assisted gait training, TAGT Therapist-assisted gait training, BWSTT Body-Weight Supported Treadmill Training, PT Physiotherapy, AS Affected side, US Unaffected side, BBS Berg balance scale, BWS body weight support, FAC Family Assistance Centre, FIM Functional Independence Measure, FMLE, Functional Mobilisation Lower Extremities; MMAS Modified Motor Assessment Scale, SARA Scale for Assessment and Rating of Ataxia, TUG Timed Up and Go, RVGA Rivermead Visual Gait Assessment, WS walking speed, FES functional electrical stimulation, GRC scale Global rating of change scale