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Table 5 Cadence (CAD) estimation performance measures. Cadence obtained from the INDIP and the single wearable device, bias, limits of agreement (LoA) and intra class correlation (ICC(2,1)) for comparison between systems, and overall performance index for the CAD algorithms. In italic and boldface recommended algorithms. Underlined performance index indicates top-ranked algorithm for the specific cohort of that row

From: Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium

Cohort

Cadence

INDIP mean and CI [steps/min]

Single wearable device mean and CI [steps/min]

Bias and LoA [steps/min]

Absolute error [steps/min]

Relative error [%]

ICC (2, 1)

Performance index

CADA

 

 HA

86.0 [85.1, 87.0]

85.6 [84.4, 86.8]

− 0.4 [− 27.0, 26.2]

8.6 [7.9, 9.3]

10.5 [9.6, 11.5]

0.65 [0.61, 0.69]

0.538

 CHF

91.2 [89.8, 92.5]

89.8 [88.2, 91.5]

− 1.4 [− 30.7, 28.0]

9.3 [8.2, 10.3]

10.6 [9.5, 11.8]

0.63 [0.57, 0.68]

0.517

 COPD

84.6 [83.7, 85.4]

86.3 [85.2, 87.3]

1.7 [− 17.5, 20.8]

6.7 [6.2, 7.2]

8.3 [7.6, 9.0]

0.72 [0.68, 0.75]

0.644

 MS

84.6 [83.1, 86.1]

85.7 [83.9, 87.5]

1.1 [− 22.8, 25.0]

8.2 [7.3, 9.2]

10.1 [8.9, 11.3]

0.71 [0.65, 0.75]

0.594

 PD

84.8 [83.4, 86.1]

87.0 [85.4, 88.6]

2.2 [− 24.9, 29.4]

9.1 [8.1, 10.1]

11.8 [10.4, 13.2]

0.62 [0.56, 0.67]

0.520

 PFF

85.0 [83.4, 86.5]

81.6 [79.9, 83.4]

− 3.3 [− 30.6, 23.9]

8.9 [7.7, 10.0]

10.4 [9.1, 11.7]

0.60 [0.54, 0.67]

0.529

CADB

 

 HA

86.0 [85.1, 87.0]

89.8 [88.9, 90.6]

3.7 [− 16.3, 23.8]

7.1 [6.6, 7.7]

9.1 [8.3, 9.9]

0.69 [0.65, 0.72]

0.585

 CHF

91.2 [89.8, 92.5]

94.6 [93.5, 95.8]

3.5 [− 14.0, 21.0]

6.4 [5.8, 7.0]

7.7 [6.9, 8.5]

0.79 [0.76, 0.82]

0.654

 COPD

84.6 [83.7, 85.4]

89.1 [88.3, 89.9]

4.5 [− 10.4, 19.4]

6.2 [5.7, 6.6]

7.9 [7.2, 8.6]

0.71 [0.67, 0.74]

0.660

 MS

84.6 [83.1, 86.1]

88.5 [87.1, 89.9]

3.9 [− 15.2, 23.0]

7.0 [6.2, 7.8]

9.0 [7.8, 10.2]

0.72 [0.66, 0.76]

0.633

 PD

84.8 [83.4, 86.1]

89.5 [88.4, 90.7]

4.8 [− 14.3, 23.8]

7.2 [6.5, 8.0]

9.7 [8.5, 10.8]

0.69 [0.63, 0.73]

0.580

 PFF

85.0 [83.4, 86.5]

86.2 [85.0, 87.5]

1.3 [− 20.9, 23.5]

7.2 [6.3, 8.1]

8.5 [7.5, 9.5]

0.66 [0.60, 0.71]

0.584

CADC

 

 HA

86.0 [85.1, 87.0]

87.4 [86.5, 88.3]

1.4 [− 18.4, 21.2]

6.4 [5.9, 6.9]

8.1 [7.3, 8.8]

0.74 [0.70, 0.76]

0.653

 CHF

91.2 [89.8, 92.5]

92.2 [90.9, 93.5]

1.0 [− 16.9, 19.0]

5.8 [5.1, 6.4]

6.6 [5.9, 7.3]

0.82 [0.79, 0.84]

0.720

 COPD

84.6 [83.7, 85.4]

86.6 [85.8, 87.4]

2.0 [− 12.9, 17.0]

5.2 [4.8, 5.6]

6.6 [6.0, 7.2]

0.77 [0.73, 0.79]

0.693

 MS

84.6 [83.1, 86.1]

85.3 [83.9, 86.8]

0.7 [− 18.8, 20.3]

6.7 [5.9, 7.5]

8.2 [7.2, 9.2]

0.75 [0.70, 0.79]

0.644

 PD

84.8 [83.4, 86.1]

87.1 [85.9, 88.4]

2.3 [− 16.2, 20.9]

6.4 [5.7, 7.1]

8.2 [7.2, 9.2]

0.76 [0.71, 0.79]

0.653

 PFF

85.0 [83.4, 86.5]

82.0 [80.7, 83.3]

− 2.9 [− 31.5, 25.6]

8.3 [7.0, 9.5]

9.1 [7.9, 10.4]

0.44 [0.35, 0.51]

0.460

  1. HA healthy adults; PD Parkinson’s disease; MS multiple sclerosis; COPD chronic obstructive pulmonary disease; CHF congestive heart failure; PFF proximal femoral fracture; CI confidence intervals, LoA limits of agreement, ICC intra class correlation