Fig. 3From: Dysfunctional neuro-muscular mechanisms explain gradual gait changes in prodromal spastic paraplegiaProgression of minimum plantarflexion and knee angle at heel strike for simulation szenarios. Increasing levels of velocity feedback gain (orange), muscle weakness (light blue), and velocity feedback gain + muscle weakness (purple) with simulation iteration \(\omega =0\%\) to \(\omega = 100\%\) and linear fits. a) minimum plantarflexion and b) knee angle at heel strike are shown with significant spearman correlation coefficients. Asterisks indicate significant levels of: \(^{**}\): \(p<0.0056\), and \(^{***}\): \(p<0.001\). For \(\omega _h=100\%\) and \(\omega _{hw}>60\%\) optimization led to no stable walking simulationsBack to article page