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Table 2 Mean results for minimum plantarflexion and knee angle at heel strike with standard deviation (STD) for experimental (upper three rows) and simulated data

From: Dysfunctional neuro-muscular mechanisms explain gradual gait changes in prodromal spastic paraplegia

Gait feature

Minimum plantarflexion

Knee angle at heel strike

HC

– 20.8 ± 9.5***

0.8 ± 6.81***

Prod SPG4

– 13.4 ± 10.5

2.8 ± 5.7**

Man SPG4

– 8.5 ± 7.9

11.9 ± 7.9

\(\omega =0\%\)

– 17.3

2

\(\omega _h=20\%\)

– 11.4

1.9

\(\omega _h=40\%\)

– 8.4

3.8

\(\omega _h=60\%\)

– 6.2

11.5

\(\omega _h=80\%\)

– 7.3

4.3

\(\omega _h=100\%\)

n.a.

n.a.

\(\omega _w=20\%\)

– 19.05

4.3

\(\omega _w=40\%\)

– 10.82

2.77

\(\omega _w=60\%\)

– 14.52

3.27

\(\omega _w=80\%\)

– 12.59

7.95

\(\omega _w=100\%\)

– 14.63

7.63

\(\omega _{hw}=20\%\)

– 8.67

3.74

\(\omega _{hw}=40\%\)

– 9.52

4.55

\(\omega _{hw}=60\%\)

– 8.4

4.33

\(\omega _{hw}=80\%\)

n.a.

n.a.

\(\omega _{hw}=100\%\)

n.a.

n.a.

  1. Asterisks indicate significance: \(^{**}\) if \(p<0.0056\) (Bonferroni corrected with 9 feature comparisons), and \(^{***}\) if \(p<0.001\) in comparison to manifest SPG4 participants. Different levels of the velocity feedback gain (\(\omega _h\)), weakness (\(\omega _w\)), and combined velocity feedback and weakness (\(\omega _{hw}\)) are given for comparison