Gait rehabilitation machines based on programmable footplates
© Schmidt et al; licensee BioMed Central Ltd. 2007
Received: 25 April 2006
Accepted: 09 February 2007
Published: 09 February 2007
Gait restoration is an integral part of rehabilitation of brain lesioned patients. Modern concepts favour a task-specific repetitive approach, i.e. who wants to regain walking has to walk, while tone-inhibiting and gait preparatory manoeuvres had dominated therapy before. Following the first mobilization out of the bed, the wheelchair-bound patient should have the possibility to practise complex gait cycles as soon as possible. Steps in this direction were treadmill training with partial body weight support and most recently gait machines enabling the repetitive training of even surface gait and even of stair climbing.
With treadmill training harness-secured and partially relieved wheelchair-mobilised patients could practise up to 1000 steps per session for the first time. Controlled trials in stroke and SCI patients, however, failed to show a superior result when compared to walking exercise on the floor. Most likely explanation was the effort for the therapists, e.g. manually setting the paretic limbs during the swing phase resulting in a too little gait intensity. The next steps were gait machines, either consisting of a powered exoskeleton and a treadmill (Lokomat, AutoAmbulator) or an electromechanical solution with the harness secured patient placed on movable foot plates (Gait Trainer GT I). For the latter, a large multi-centre trial with 155 non-ambulatory stroke patients (DEGAS) revealed a superior gait ability and competence in basic activities of living in the experimental group. The HapticWalker continued the end effector concept of movable foot plates, now fully programmable and equipped with 6 DOF force sensors. This device for the first time enables training of arbitrary walking situations, hence not only the simulation of floor walking but also for example of stair climbing and perturbations.
Locomotor therapy is a fascinating new tool in rehabilitation, which is in line with modern principles of motor relearning promoting a task-specific repetitive approach. Sophisticated technical developments and positive randomized controlled trials form the basis of a growing acceptance worldwide to the benefits or our patients.
The restoration of gait for patients with impairments of the central nervous system (CNS), like e.g. stroke, spinal cord injury (SCI) and traumatic brain injury (TBI) is an integral part of rehabilitation and often influences whether a patient can return home or to work. Particularly stroke is the leading cause for disability in all industrialized countries, the incidence is approximately one million patients in the European Union each year [1, 2]. Modern concepts of motor learning favor a task specific training, i.e. to relearn walking, the patient should ideally train all walking movements, needed in daily life, repetitively in a physically correct manner . Conventional training methods based on this approach, proved to be effective, e.g. treadmill training , but they require great physical effort from the physiotherapists to assist the patient, so does even more training of free walking guided by at least two physiotherapists. Assisted gait movements other than walking on even floor, like for instance stair climbing, are practically almost impossible to train, due to the overstrain of the physiotherapists. Assistive training devices, in particular those based on the concept of programmable footplates, may offer a solution to these shortcomings.
Hemiparesis is the typical sequelae following stroke, three months after the incident one third of the surviving patients has not yet regained independent walking ability, and those ambulatory walk in a typical asymmetric manner, as they avoid to load the paretic limb. At the same time their walking velocity and endurance are markedly reduced. Stairs, sudden obstacles, uneven terrain or other perturbations further challenge the patients' gait ability outside the clinic. The rehabilitation process toward regaining a meaningful mobility can be divided into three phases :
1. the bedridden patient has to be mobilized into the wheelchair,
2. restoration of gait,
3. and improvement of gait in order to meet the requirements of daily mobility.
For the first phase, an early mobilization policy is generally accepted, i.e. over the edge of the bed the patient is transferred into the chair as soon as possible. The second phase, restoration of gait, has seen major changes in the last decade, in particular with the introduction of a task-specific repetitive gait training approach. During this phase gait rehabilitation machines come into play, especially for severely affected patients. They relieve the physiotherapists from hard manual labour and enable an increase in training intensity for the patients, the latter is an important factor in motor learning. Until the beginning of the third phase patients have regained walking ability and can further improve it now by training of free walking. Depending on the patients learning success, support by physiotherapists may still be necessary during this phase. The following chapters mainly refer to the second phase.
Proponents of so called neurophysiological treatment concepts (Bobath, PNF, Brunnstroem, Vojta) aimed at the restoration of a most physiological gait pattern . Bobath therapists, the most widely accepted treatment concept in Europe, intended to inhibit an increased muscle tone (spasticity) by gently mobilizing the paretic limbs and opposing synergistic movements, and to repeat quasi in short form the statomotoric development of a child as prerequisite for the final goal of a most natural walking habit. Accordingly, tone-inhibiting manoeuvres and motor tasks while lying, sitting or standing dominated therapy sessions of patients, who desperately wished to walk. Some therapists even recommended to sit again into the wheelchair being afraid of the patient familiarizing with his bad gait quality.
This policy collided with modern task-specific repetitive concepts of motor learning, emerging in the early nineties, i.e. who wants to relearn walking has to walk. Locomotor therapy by treadmill training with partial body weight support was a first step in this direction. The patient wore a harness to substitute for deficient equilibrium reflexes, part of his body weight was relieved to compensate for the paresis of the impaired lower limb, and the motor-driven treadmill enforced locomotion [7, 8]. Wheelchair-bound patients could thus practice up to 1000 steps during a 30 min session as compared to 50 to 100 at maximum during a conventional therapy session. Two therapists assisted the patients' gait, sitting alongside to place the paretic limb, to ensure an initial contact with the heel, to prevent a knee hyperextensor thrust and to control for a symmetric step length. Standing behind the patient, a second therapist shifted the weight according to stance/swing phase, promoted hip extension and trunk erection. The concept of locomotor therapy was striking: massive gait practice to activate spinal and supraspinal pattern generators and an efficient cardiovascular training of the deconditioned and often multimorbide patients.
A major clinical study in order to investigate the locomotor therapy concept, was an A-B-A study (A: treadmill, B: physiotherapy, each phase lasted 3 weeks) which showed that the chronic non-ambulatory stroke patients exclusively improved their gait ability and walking velocity during the A-phases . Those results clearly supported the task-specific training concept, as the physiotherapy had followed a very conservative Bobath approach with the practice of gait itself minimal.
Subsequent RCTs in acute non-ambulatory patients accordingly compared treadmill training with gait practice on the floor. The results were unexpected: treadmill training and gait practice did not differ with respect to the restoration of gait, and a Cochrane meta analysis came to the conclusion that locomotor therapy on the treadmill was not superior . What had happened? Due to the comparable effort for the therapists assisting the patients' gait on the treadmill and on the floor, the number of steps practiced probably had not differed between the two conditions. Unfortunately neither article reported exact numbers, but it was not uncommon that therapists stopped the treadmill treatment after 300 to 400 steps due to fatigue.
Gait Rehabilitation Machines
Until now three other prototypes using the latter approach were designed [12–14]. The machines allow more effective training sessions, where patients can train up to 1000 steps within a typical training session of 15–20 min, whereas during manually assisted training only approx. 100 steps/session were performed. A second major effect is the relief of the physiotherapists, who can now concentrate on training supervision.
The aforementioned machines apply two different approaches to gait rehabilitation: the exoskeleton type machines, which need to be operated in combination with a treadmill. They require the patient to be fixed to the robot kinematics from the pelvis on downward along the legs, which results in a bilateral and proximal guidance. The patients body weight is carried by the treadmill. Due to the complete fixture of the patient to the machine, the device is not designed for physical access of the therapist during the training session, but for fully automated training sessions.
In contrast the Gait Trainer GT I applies the principle of movable footplates, where each of the patients feet is positioned on a separate footplate whose movements are controlled by a planetary gear system, simulating foot motion during stance and swing. Cadence and stride length could be set individually. Further, the vertical and horizontal movements of the centre of mass were controlled via ropes attached to the harness. This machine concept leads to a bilateral and distal guided gait training. The patients knees are not fixed, in order to allow the therapists access for physical contact with the patient, which is an important factor in rehabilitation [2, 15] and also allows him to do minor corrections of the knee motion if needed. Alternatively other techniques to stabilize knee motion like Functional Electrical Stimulation (FES) or separate mechanical fixtures can be applied if necessary. We optionally used a programmable 8-channel FES system enabling the individually adjusted stimulation of lower limb muscles, in order to control the paretic knee or to assist push-off during the terminal stance phase. Another important reason for this design approach is that the number of constraints on natural hip and leg motion (muscles and joints) and the large number of degrees of freedom of the human leg should be kept as low as possible. The tighter the attachment of the leg to a robot arm with a technically limited number of degrees of freedom, the more constrained the resulting leg motion.
To the best of our knowledge, no other gait rehabilitation device could achieve comparable results, even though in the DEGAS study as well as in all other GT I studies the machine was run in position controlled mode.
Why did the gait trainer lead to a better outcome than the manually assisted treadmill in previous RCTs? Again, training intensity was the most likely explanation: on the GT I the patients could continuously practice 800 to 1000 steps per session, as the effort of the therapists was drastically reduced. RCTs in Slovenia , Korea , and Hong Kong  confirmed the DEGAS results for acute non-ambulatory stroke patients. For chronic, ambulatory patients a Finnish study  revealed that an intensive gait training either on the machine or on the floor and even outside the clinic were equally effective. These findings support the intensity principle as ambulatory patients were encouraged to train as many steps as possible in their conventional physiotherapy sessions.
Programmable Footplate based Gait Rehabilitation Robot
The HapticWalker accomplishes the paradigm for optimal training, because it is the first gait rehabilitation device which is not restricted to training of walking on even ground. In contrast to all treadmill bound machines, it enables the patient to train arbitrary gait trajectories and daily life walking situations. It is also distinct from the small number of haptic foot device prototypes, which have been built by groups in the USA [30, 31] and Japan [32, 33] for healthy subjects (e.g. virtual soldier training). Unlike these machines, which are designed to provide contact between foot and footplate only during stance phase, the HapticWalker comprises a translatory and rotatory footplate workspace needed for permanent foot attachment along arbitrary walking trajectories during all phases of gait. This is an essential feature for gait rehabilitation machines. A group at Rutgers University  recently built a small walking simulator testbed with permanent foot attachment based on two small Stuart platforms. Those motion platforms, which are also called hexapod platforms, are based on a parallel kinematics principle and often used for flight simulators. The workspace and dynamic range of the small Stewart platforms the group designed are very limited and do not allow for natural walking profiles.
The HapticWalker footplate dynamics were designed such that not only smooth foot motions at moderate walking speeds can be accomplished, but also the realistic simulation of walking speeds of up to 5 km/h and 120 steps/min. This takes into account different gait rehabilitation strategies, the most widely practised starts with walking speeds of less than 1 km/h and gradually increases gait speed and cadence up to normal walking velocities of 4–5 km/h depending on the patients learning success . In contrast some clinical groups in the US  favor the application of high walking speeds and cadences of 4–5 km/h right from the very beginning of therapy. The purpose of high footplate dynamics was also to enable the realistic simulation of gait perturbations like stumbling, sliding and other asynchronous walking events. Regarding usability, the HapticWalker is designed to allow therapists access to the patient for physical contact during training from all sides, as well as facilities for easy patient transfer into the machine, since they are usually bound to the wheelchair. Technical details of the machine design, robot kinematics, control system, algorithms for motion generation, haptic features, therapist user interface and safety aspects can be found in  and the referring references cited in there.
Efficient gait rehabilitation requires the CNS impaired patient to practise as many different daily life walking trajectories as intensive as possible. The HapticWalker, a generic robotic walking simulator based on the principle of programmable footplates, is the first device to fulfil these requirements by allowing the training of arbitrary walking situations and foot trajectories (e.g. even ground, stair climbing up/down, perturbations like stumbling/sliding). The task specific gait rehabilitation concept of repetitive foot motions on natural trajectory profiles was proved by different clinical research groups worldwide. Our group coordinated the DEGAS study, the largest clinical multi-center RCT study for gait rehabilitation machines worldwide. It investigated the movable footplate based electromechanical Gait Trainer GT I including its position controlled, bilateral and distal approach compared to conventional gait training. The study was finished recently and fully proved the definitive advantages and benefits of this gait rehabilitation approach for the patients. The robotic gait trainer HapticWalker extends this concept to programmable footplates, thus it optimally fulfills the requirements of the task specific training paradigm. A full working prototype of the Haptic Walker was successfully developed and built, it is currently being clinically tested after receiving full approvals by the German Technical Committee for Medical Devices (TÜV) and the Charité ethics board. A clinical study with focus on staircase walking in addition to even ground walking was started in order to evaluate the machine. First trials with stroke and SCI patients are very promising and give reason to anticipate even better results than the ones seen in the DEGAS study.
The authors gratefully acknowledge funding by the German Ministries for Education and Research (BMBF) and Economy and Labour (BMWA) as well as by the German Science Foundation (DFG).
- Kolominsky-Rabas PL, Sarti C, Heuschmann PU, Graf C, Siemonsen S, Neundoerfer B, Katalinic A, Lang E, Gassman KG, von Stockert TR: A prospective community-based study of stroke in Germany: the Erlangen Stroke Project (ESPro): incidence and case fatality at 1, 3, and 12 months. Stroke 1998, (29):2501-2506.Google Scholar
- Carr JH, Shepherd RB: Neurological Rehabilitation: Optimizing Motor Performance. Butterworth-Heinemann; 1998.Google Scholar
- Asanuma H, Keller A: Neurobiological basis of motor learning and memory. Concepts Neuroscience 1991, 2: 1-30.Google Scholar
- Hesse S, Helm B, Krajnik J, Gregoric M, Mauritz KH: Treadmill training with partial body weight support: influence of body weight release on the gait of hemiparetic patients. J Neurol Rehab 1997, 11: 15-20.Google Scholar
- Carr JH, Shepherd RB: A Motor Relearning Programme for Stroke. 2nd edition. Aspen Publishers; 1987.Google Scholar
- Sackley CM, Lincoln NB: Physiotherapy for stroke patients: a survey of current practice. Physiother Theor Pract 1996, (12):87-96.Google Scholar
- Dietz V, Colombo G, Jensen L: Locomotor activity in spinal man. Lancet 1994,344(8932):1260-1263.View ArticlePubMedGoogle Scholar
- Hesse S, Bertelt C, Jahnke MT, Schaffrin A, Baake P, Malezic M, Mauritz KH: Treadmill training with partial body weight support as compared to physiotherapy in non-ambulatory hemiparetic patients. Stroke 1995, 26: 976-981.View ArticlePubMedGoogle Scholar
- Moseley AM, Stark A, Cameron ID, Pollock A: Treadmill training and body weight support for walking after stroke. The Cochrane Database of Systematic Reviews 2005., 3:Google Scholar
- Hesse S, Uhlenbrock D: A mechanized gait trainer for restoration of gait. Journal of Rehabilitation Research & Development 2000,37(6):710-708.Google Scholar
- Colombo G, Joerg M, Schreier R, Dietz V: Treadmill training of paraplegic patients using a robotic orthosis. Journal of Rehabilitation Research & Development 2000,37(6):693-700.Google Scholar
- HealthSouth Corporation: Powered gait orthosis and method of utilizing same. US Patent: 6,689,075 2004.Google Scholar
- Reinkensmeyer DJ, Wynne JH, Harkema SJ: A robotic tool for studying locomotor adaptation and rehabilitation. Proceedings of the IEEE Engineering in Medicine and Biology Conference (EMBC), Houston, TX, USA 2002.Google Scholar
- Veneman JF, Ekkelenkamp R, Kruidhof R, van der Helm FCT, van der Kooij H: Design of a Series Elastic- and Bowdencable-based actuation system for use as torque-actuator in exoskeleton-type training. Proceedings of the IEEE 9th International Conference on Rehabilitation Robotics (ICORR), Chicago, IL, USA 2005, 496-499.Google Scholar
- Montagu A: Touching: The Human Significance of the Skin. 3rd edition. Harper & Row Publishers; 1986.Google Scholar
- Hesse S, Werner C, Uhlenbrock D, v Frankenberg S, Bardeleben A, Brandl-Hesse B: An Electromechanical Gait Trainer for Restoration of Gait in Hemiparetic Stroke Patients: Preliminary Results. Neurorehabilitation and Neural Repair 2001, 15: 39-50.View ArticlePubMedGoogle Scholar
- Wirz M, Zemon DH, Rupp R, Scheel A, Colombo G, Dietz V, Hornby TG: Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: a multicenter trial. Arch Phys Med Rehabil 2005,86(4):672-680.View ArticlePubMedGoogle Scholar
- Werner C, Pohl M, Holzgrefe M, Kroczek G, Mehrholz J, Wingendorf I, Hölig G, Hesse S: "DEGAS" – Deutsche Gangtrainerstudie zur Evaluation des Gangtrainer GT I in Kombination mit Physiotherapie im Vergleich zur Physiotherapie alleine bei akuten Schlaganfallpatienten. Neurologie & Rehabilitation 4/2004, Proceedings of 'Evidence-Based Medicine in Neurorehabilitation', 3rd Joint Congress of the Swiss, Austrian and German Societies of Neurological Rehabilitation, Zurich, Switzerland 2004, S45.Google Scholar
- Pohl M, Werner C, Holzgraefe M, Kroczek G, Mehrholz J, Wingendorf I, Hölig G, Koch R, Hesse S: Repetitive locomotor training and physiotherapy improve walking and basic activities of daily living after stroke: a single-blind, randomized multicentre trial (DEutsche GAngtrainerStudie, DEGAS). Clinical Rehabilitation 2007, 21: 17-27.View ArticlePubMedGoogle Scholar
- Holden MK, Gill KM, Magliozzi MR, Nathan J, Piehl-Baker L: Clinical gait assessment in the neurologically impaired: reliability and meaningfulness. Physical Therapy 1984, 64: 35-40.PubMedGoogle Scholar
- Collen FM, Wade DT, Gradshaw CM: Mobility after stroke: reliability of measures of impairment and disability. International Disability Studies 1990, 12: 6-9.View ArticlePubMedGoogle Scholar
- Mahoney FI, Barthel DW: Functional evaluation: The Barthel Index. Maryland State Medical Journal 1965, (14):56-61.Google Scholar
- Globokar D: Gait trainer in neurorehabilitation of patients after stroke. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine (ISPRM) 2005, Sao Paulo, Brazil 2005, 166. Abstract 987-1Google Scholar
- Jang SJ, Park SW, Kim ES, Wee HM, Kim YH: Electromechanical gait trainer for restoring gait in hemiparetic stroke patients. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine (ISPRM) 2005, Sao Paulo, Brazil 2005, 270. Abstract 909-1Google Scholar
- Li LSW, Tong RKY, Ng MFW, So EFM: Gait training by mechanical gait trainer and functional electrical stimulation for subacute stroke patients: a randomised controlled study. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine (ISPRM) 2005, Sao Paulo, Brazil 2005, 78. Abstract 347-1Google Scholar
- Peurala SH, Tarkka IM, Pitkänen K, Sivenius J: The effectiveness of body weight-supported gait training and floor walking in patients with chronic stroke. Arch Phys Med Rehabil 2005, 85: 1557-1564.View ArticleGoogle Scholar
- Lordahl DS, Archer EJ: Transfer effects on a rotary pursuit task as a function of first task difficulty. Journal of Experiomental Psychology 1958, 56: 421-426.View ArticleGoogle Scholar
- Cormier SM, Hagman JD: Transfer of Learning: Contemporary research applications. Academic Press, New York; 1987.Google Scholar
- Schmidt RA, Lee TD: Motor Control and Learning. 3rd edition. Human Kinetics Publishers, Inc; 1998.Google Scholar
- Roston GP, Peurach T: A whole body kinesthetic display device for virtual reality applications. Proc of IEEE Intl Conf on Robotics & Automation (ICRA), Albuqerque, NM, USA 1997, 3006-3011.View ArticleGoogle Scholar
- Hollerbach JM: Locomotion Interfaces. In Handbook of Virtual Environments: Design, Implementation, and Applications. Edited by: Stanney KM. Lawrence Erlbaum Associates, Inc; 2002:239-254.Google Scholar
- Iwata H, Yano H, Nakaizuni F: GaitMaster: A Versatile Locomotion Interface for Uneven Virtual Terrain. Proc of IEEE Virtual Reality Conference, Yokohama, Japan 2001, 131-137.Google Scholar
- Shiozawa N, Arima S, Makikawa M: Virtual Walkway System and Prediction of Gait Mode Transition for the Control of the Gait Simulator. Proceedings of the IEEE Engineering in Medicine and Biology Conference (EMBC), San Francisco, CA, USA 2004.Google Scholar
- Boian RF, Bouzit M, Burdea GC, Deutsch JE: Dual Stewart Platform Mobility Simulator. Proceedings of the IEEE Engineering in Medicine and Biology Conference (EMBC), San Francisco, CA, USA 2004, 4848-4851.Google Scholar
- Behrman AL, Harkema SJ: Locomotor training after human spinal cord injury: A series of case studies. Physical Therapy 2000,80(7):688-700.PubMedGoogle Scholar
- Schmidt H, Hesse S, Bernhardt R, Krüger J: HapticWalker – A novel Haptic Foot Device. ACM Transactions on Applied Perception 2005,2(2):166-180.View ArticleGoogle Scholar
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