From: A review of movement disorders in chemotherapy-induced neurotoxicity
Authors | Population | Procedures | Examined variables | Results/Conclusions | |
---|---|---|---|---|---|
PAT | CT | ||||
Osumi 2019 [69] | Cancer patients with perceived numbness from chemotherapy: N = 12 | Age-matched controls: N = 12 | Electromagnetic motion tracking system measured kinematic data while participants completed reach-to-grasp movement | Kinematic analysis: Reach and grasp movement (jerk index) Von Frey filament Numbness rating Motor function: # of grasp and release movements can be performed in 10 s | PAT group had impaired grasp jerk index compared to controls, but no significant difference was found in reach jerk index. Grasp jerk index was directly correlated with poor scores in sensory tests and hand grip-release test. |
Reinders-Messelink 2001 [70] | Pediatric cancer patients receiving vincristine for acute lymphoblastic leukemia: N = 11 | Age-matched healthy children: N = 11 | A digitizer tablet and a force sensing pen measured quality of hand drawing during drawing tasks of different complexity | Quality of hand drawing: velocity, fluency, pause durations and pen pressure | PAT group drew slower, with longer pause durations and increased drawing pressure. PAT group were able to overcome the problems after vincristine was withdrawn, except for the increased drawing pressure. |