- Open Access
The SmartHand transradial prosthesis
© Cipriani et al; licensee BioMed Central Ltd. 2011
Received: 25 October 2010
Accepted: 22 May 2011
Published: 22 May 2011
Prosthetic components and control interfaces for upper limb amputees have barely changed in the past 40 years. Many transradial prostheses have been developed in the past, nonetheless most of them would be inappropriate if/when a large bandwidth human-machine interface for control and perception would be available, due to either their limited (or inexistent) sensorization or limited dexterity. SmartHand tackles this issue as is meant to be clinically experimented in amputees employing different neuro-interfaces, in order to investigate their effectiveness. This paper presents the design and on bench evaluation of the SmartHand.
SmartHand design was bio-inspired in terms of its physical appearance, kinematics, sensorization, and its multilevel control system. Underactuated fingers and differential mechanisms were designed and exploited in order to fit all mechatronic components in the size and weight of a natural human hand. Its sensory system was designed with the aim of delivering significant afferent information to the user through adequate interfaces.
SmartHand is a five fingered self-contained robotic hand, with 16 degrees of freedom, actuated by 4 motors. It integrates a bio-inspired sensory system composed of 40 proprioceptive and exteroceptive sensors and a customized embedded controller both employed for implementing automatic grasp control and for potentially delivering sensory feedback to the amputee. It is able to perform everyday grasps, count and independently point the index. The weight (530 g) and speed (closing time: 1.5 seconds) are comparable to actual commercial prostheses. It is able to lift a 10 kg suitcase; slippage tests showed that within particular friction and geometric conditions the hand is able to stably grasp up to 3.6 kg cylindrical objects.
Due to its unique embedded features and human-size, the SmartHand holds the promise to be experimentally fitted on transradial amputees and employed as a bi-directional instrument for investigating -during realistic experiments- different interfaces, control and feedback strategies in neuro-engineering studies.
The hand is a powerful tool and its loss causes a severe psychological and physical drawback. Despite the significant impact of losing a hand, numbers of amputees requiring a prosthesis are too small to push manufacturers to innovate their products, so that both control interfaces and mechanisms have barely changed in the past 40 years . The most technologically advanced prostheses are myoelectric ones: one or two degrees of freedom (DoFs) motorized hands (or hooks) are activated by antagonist residual muscle contractions where the electromyographic (EMG) signal is picked-up by surface electrodes in the prosthetic socket and processed to functionally open and close the hand (or pronate/supinate the wrist). These prosthetic hands, commercially available since the early 1970's and produced by different manufacturers (Otto Bock, Austria; RSL Steeper, UK; Motion Control, Utah; LTI, Massachusetts), are robust, weigh up to 600 g and are able to impart up to 100 N to objects due to their pincer-like shape. Low functionality, cosmesis and controllability have been considered as the main drawbacks for such devices  and surveys on their usage reveal that 30 to 50% of upper limb amputees do not use them regularly . The lack of musculoskeletal and proprioceptive sensory feedback in myoelectric prostheses is one of the main reasons for their rejection : a stump with intact sensory feedback fitted with a body-powered prosthesis (that transmits vibration and grasping force to the stump through the harness) is often more functional than a myoprosthesis with no purposely delivered sensory feedback . Some of these drawbacks could be overcome by a product that recently entered the market. In July 2007 a Scotland based company, Touch Bionics, has launched a novel multi-articulated prosthesis: the i-LIMB hand. This is the first-to-market prosthesis with five individually-powered digits and a thumb abduction/adduction passive movement. Consequently the hand is capable of different grasping patterns, nevertheless it still uses a traditional two-input EMG system to simultaneously open and close all fingers. Over and above, no sensory feedback is delivered to the wearer.
The development of a more functional and naturally controlled prosthetic hand has been an active research field for decades and is still one of the big research challenges in rehabilitation, for which a tight collaboration between engineers, neuroscientists, medical doctors and patients is required. The most natural/intuitive control is one that is driven by neural signals tapped from the human central (CNS) or peripheral nervous system (PNS). In particular with the use of a neural interface directly connected to the PNS or CNS that is able to replace the sophisticated bidirectional link between the brain and the hand actuators and sensors, an advanced robotic limb might be able to put user intent into action and provide the user with perception of the hand itself by delivering sensory proprioceptive and exteroceptive information . On this basis, the sensors to be endowed in advanced prosthetic hands should not be chosen and used just for closing automatic control loops (as in commercial devices), but also with the aim of delivering afferent information to the user through an adequate user-prosthesis interface (UPI).
One of the most challenging tasks in this field is certainly that of developing a dexterous intrinsic prosthetic hand, i.e. a hand that contains all its functional components (actuators, sensors, electronics, etc.), that can be used for patients after a distal transradial amputation. In the past decades several examples have been developed in research: the Sven hand, the Belgrade, the Southampton, the MARCUS, the TBM, the RTR II, the SPRING, the MANUS, the Ultralight hands in Forschungszentrum Karlsruhe, the Soft hand, the KNU hand [6–16]. Even if these prototypes differ in mechanisms, sensory equipment, performance and objectives, they all share the requirements of being low power, low weight, still allowing a number of prehension patterns useful in activities of daily living (ADLs). Such constraints were met by the use of different underactuated mechanisms (fundamental for reducing the number of actuators) and clutching systems (to save power once the grasp is stable): i.e. the two basic mechanical components in a prosthetic hand. All these intrinsic hands have been designed with the aim of being controlled by EMG surface electrodes or other intelligent control schemes , so that in most of them the sensorization is limited and mainly employed for the low-level control of the grasp. Even if some attempts to connect them to non-invasive feedback systems have been done, [18–20], most of these prototypes (with the exception of the Southampton-REMEDI hand, that contains sufficient active DoFs for different prehensile patterns, and an extended sensory system) would not be suitable if neurally interfaced with a large bandwidth link due to either their limited (or inexistent) sensorization or limited dexterity . Other significant research even if related to extrinsic actuated hands to be used as research prostheses platforms include the CyberHand , the Yokoi hand , and Vanderbilt University prototypes [23, 24]. In August 2008, researchers and companies supported by DARPA Revolutionizing Prosthetics Program (RPP) 2009  have presented preliminary results at the Myoelectric Controls/Powered Prosthetics Symposium (MEC) held in Fredericton, NB, Canada. In particular: the RPP intrinsic hand , and a prototype from the Rehabilitation Institute of Chicago  were presented. Later, in May 2010 new prototypes or products from manufacturers were firstly exhibited at the ISPO (Intl. Society on Prosthetics and Orthotics) world congress held in Leipzig, Germany: in particular the Ottobock Michelangelo hand, the RSL Steeper Bebionic hand, and the second release of i-Limb, namely Pulse, from Touch Bionics.
The goal of this work was to design and develop a new, lightweight, dexterous, sensorized prosthetic hand with intrinsic actuation, i.e. a self-contained, transradial prosthetic hand able to be fitted in subjects with an amputation level, long below the elbow. This hand is meant to be clinically experimented by amputees employing different levels of interfaces, in order to investigate the effectiveness of more natural and intuitive control and feedback strategies. Interfaces under investigation will range from non-invasive EMG control and sensory substitution systems (as in [28, 29]), to neural electrodes directly implanted into the PNS (as in ).
To this twofold aim a prototype with advanced integrated actuation and sensory features, compared to previous works and state of the art, was developed and successfully tested. This paper presents an overview of the design (partially covered in [21, 31] and ) and focuses on the experimental characterization and discussion of the prototype performance, which is the unique contribution of this work. It demonstrates that due to its advanced embedded features and human-size, the SmartHand could be experimentally fitted on transradial amputees and employed as a bi-directional instrument for investigating -during realistic experiments- different interfaces, control and feedback strategies. Therefore the development of this hand opens up promising possibilities for the development of intuitive UPI and upper limb prosthetics in general.
Requirements and Design Principles
Power grasps (used in approximately 35% of the ADLs);
Precision grasps (30%);
Lateral grasp (20%);
Index pointing (useful for pressing buttons, etc.);
Basic gestures (counting).
anthropomorphism: i.e. size and weight (about 400 g), number and distribution of articulations, number and distribution of independently actuated DoFs;
static and dynamic biomimetism ;
sensorization: types of sensors and distribution ;
performance: speed (whole hand closing in less than 2 seconds) and grasping force (able to stably handle everyday objects).
The hand sensory system is designed to be used both for the automatic control of the grasp (action) and for delivering sensory information to the user (perception) by means of UPIs with different degrees of invasiveness. In fact, recent studies have preliminarily shown the possibility of delivering force and position afferent information directly to the PNS, by means of an implanted neural interface [30, 37], or touch, pressure and temperature sensations by employing a non-invasive sensory feedback system to redirected parts of the body after targeted reinnervation procedure . More recently it has been shown how amputees can be made to experience a rubber hand as part of their own body by simply tricking their brain using the so-called rubber hand illusion; a simple method based on a prosthesis equipped with tactile sensors for transferring sensations from the stump to the prosthesis was then outlined. Based on the reported studies, a sensor set that provides three different types of information, namely, position, tactile/pressure and force, was chosen. The spatial distribution of sensors in the hand (shown in Figure 1B) is similar to the natural concentration: higher on the independently actuated thumb and index fingers . There are 32 proprioceptive and exteroceptive sensors based on traditional technologies embedded in the hand: 15 Hall effect-based angle sensors (integrated in all the finger joints), 5 strain gauge based tendon tension sensors (as in ) integrated in the fingertips (thus measuring the grasping force of each finger), 4 current sensors (one for each motor) and 4 optical tactile/pressure analog sensors (based on ) in the intermediate and proximal phalanxes of the thumb and index. Actuation units are also equipped with position sensors (either a resistive potentiometer or a digital encoder, measuring the released tendon length) and pairs of digital proximity sensors acting as limit switches (avoiding mechanical collisions). A detailed presentation of the SmartHand sensory system features is presented in .
Robotic Hand Design
The hand is composed of a number of elements containing mechanisms, sensors and necessary electronics. Specifically it consists of: (i) 5 underactuated fingers, (ii) 2 capstan-based actuators driving the thumb and index flexion/extension (connected to M1 and M2), (iii) 1 adaptive grasping mechanism driving the middle-ring-little fingers (AGM connected with M3), and (iv) the thumb abduction/adduction mechanism (on M4). Each part is presented in detail in the following sub-sections.
Underactuated Sensorized Finger
In a majority of research projects on prosthetic hands, and in general in robotic hands, non-back-drivability is achieved by means of screw/lead screw pairs (as in all previously mentioned intrinsic hands with the exception of ). This is actually a simple to build mechanism but its efficiency is very low. To overcome such problem, a miniaturized high efficiency non-back-drivable mechanism (NBDM) based on wedge phenomena was developed for the SmartHand (described in detail in ).
a small-sized brushed DC motor (Faulhaber Minimotor, model 1319) with integrated planetary gear head (491:1);
a spur gear couple;
the developed NBDM;
a 6,5 mm radius capstan, which is finally connected to a commercial long rotational life resistive trimmer able to measure the released tendon length;
2 Hall effect proximity sensors (Allegro MicroSystems Inc, model A3213) acting as limit switches, that together with a magnet fixed on one spur gear limit the tendon release.
A stainless steel microcable tendon is wound around the capstan, and runs into round steel wire spirals from the actuator output to the finger metacarpus. The system is completed by a round PCB topping the potentiometer (Figure 2B), containing filters for removing electrical noise from the position signal. Two identical actuation systems as the one described are housed in the palm and employed to independently actuate the thumb and index fingers flexion/extension movement.
Adaptive Grasping Mechanism
This system is an improvement of the non-back-drivable adaptive grasping mechanism proposed by Massa et al. . It drives the simultaneous flexion/extension of middle, ring and little fingers, as well as their adaptation to the object, allowing a stable, multiple contact grasp as in the natural hand. In this mechanism, the screw/lead screw could not be avoided: three tendons are connected to a linear slider by means of three compression springs (scheme in Figure 2C). The slider moves along the screw by means of a screw/lead screw pair and pulls (or releases) the tendons. Two limit switches are assembled along the screw, in order to limit the length of cable released. By means of the compression springs, during a general grasp, adaptation to the object of the three fingers is obtained: when the first finger comes in contact with the object, the relative spring starts to compress; the slider is free to continue its motion and the other fingers can flex reaching the object. If high forces are required, compression springs behave as a rigid link and the force is transmitted from the slider to the fingers. The actuation unit is composed of a brushed DC motor (Faulhaber Minimotor, Model 1331) with integrated planetary gear-head (reduction 16:1) and integrated encoder, a spur gear couple (reduction 1:2) and a non-back-drivable screw-lead screw coupling (pitch 0.7 mm) where the slider runs.
All components of the hand are housed inside a supporting skeleton machined in Ergal alloy aluminium. The base of the skeleton integrates a standard myoprosthesis wrist adapter which includes a 4 wire bus for communication. The SmartHand control board (see section 3.6) is placed on the motors (cf. Figure 3), and covered by a plane carbon fibre plate acting as the palm of the hand.
Flexible Controller & Communication
The main function of the internal software implemented in the LLMC is to provide all the necessary low level motor control functions (i.e. force control, position control modes, sleep mode). Therefore the microcontroller acts as a double finite-state machine (one for each motor) where the transitions between the different modes are triggered by HLHC commands coming from the SPI2 bus (Figure 4). The HLHC is in charge of sequencing LLMC functions to obtain meaningful operation of the hand (i.e. grasps and gestures) after an external command, to provide artificial sensory information to the UPI, to manage power modes and handle errors.
Current is delivered to the DC motors using integrated H-bridges and measured by a commercial current sensor (INA138, Texas Instruments). Two different power suppliers, one for the motors (12 V) and one for the controller (6 V) are needed. Since power budget is a key issue in prosthetics, particular attention has been paid to design a flexible architecture able to manage low power modes; three different voltage regulators are used. The first one, named as PIC V REG in the schematic of Figure 4, supplies the main components of the circuit, i.e. the three microcontrollers; its regulated output, is shut down by an external-world digital line (EN P). A second and a third regulator, named Finger V REG and Actuators Sensors V REG , are employed to supply the sensors embedded in the fingers and the sensory equipped actuators, respectively. These supplies, directly controlled by the HLHC (using EN F and EN A), may be used in switching modality when possible, in order to reduce power consumption. Moreover, the selected microcontrollers can operate in power-managed modes, thus saving energy.
A communication protocol for the RS232 bus based on a 115200 baud rate, has been developed. Basically it is a master-slave protocol where the hand behaves as a slave and the external world (either a PC for diagnosis or a UPI) as a master. Commands are divided into three main types: motor commands (for driving fingers in position or force control), sensor readings and automatic grasps. Without any particular firmware code optimization, all readings are served by the HLHC within a measured delay of 400 μs. This is a very short value that could allow implementing and closing control loops even by algorithms running on external systems. Internal control loops (position and force based on tendon tension) update errors every 1 ms (i.e. 4 independent and simultaneous loops running at a measured frequency of 1 KHz).
Automatic grasps are modelled on natural grasping. When an external unit (e.g. a control interface) invokes a grasping primitive (e.g. the lateral grasp), two different phases are sequenced by the HLHC: the preshaping and the grasping (closure) phase. After preshaping the desired finger tendon force is selected according to the grasping primitive. In the second phase, the prosthesis closes the involved fingers (in the lateral grasp example only the thumb closes) using tendon tension force control until the desired global tight force is reached. Both preshaping postures and desired grasping forces are set a priori and are based on the grasping primitive. For a detailed description of the automatic grasp controller refer to .
Pictures of the SmartHand are presented in Figure 6, where a qualitative comparison with a traditional prosthesis and with the healthy hand of a transradial amputee are shown (a detailed comparison of the SmartHand with other research and commercial hands is presented in ). The weight of this hand is close to the natural hand weight and comparable to actual commercial prostheses: 530 g. This does not include the standard wrist attachment (145 g) and batteries (that are usually hosted in the prosthetic socket proximally to the residual limb). Performance with relation to the prosthesis requirements listed in the Requirements and Design Principles section and to practical usage have been evaluated. This comprehensive list of measured features includes: (i) finger dynamics, (ii) speed, (iii) grasping capabilities, (iii) grasping force, (iv) degree of adaptability, (v) supporting grasp capabilities and (vi) power consumption.
Finger Dynamics and Speed
as required, the finger kinematics is similar to the natural one while closing in free space (i.e. MCP joint speed is higher than the PIP one, and the DIP is the slowest; ), therefore the hand is able to perform stable grasps with multiple contact points ;
minimum closing time is acceptable and comparable with commercial prostheses being only 1.47 s ;
Actuation units minimum closing and opening times
Closing time [s]
Opening time [s]
Grasping Force & Degree of Adaptability
With the present underactuated, adaptive hand, stability in power grips is achieved by means of a multi-contact grasp differently from commercial prostheses where high forces are applied on few points ; in any case, the important issue for an amputee is the ability of stably grasping objects without slippage.
The maximum load that the hand could grasp in a power grasp prehensile form has been measured using the following setup. For all these measurements fingers were covered with silicone tubes (as those shown in Figure 6; hardness durometer 5 A) behaving as a cosmetic covering and improving friction between aluminum fingers and the (plastic) objects. A 36 mm diameter, 12 cm long, plastic (delrin) cylinder (180 g), connected by means of a steel cable to a 20 kg (full scale) mono-axial load cell, was grasped (at maximum strength) using the automatic grasp control. The hand was then switched-off (simulating a real life situation) and the cylinder was pulled out along the direction of its axis at a relatively high speed (about 130 mm/s), with the palm facing upwards, while the load cell signal was acquired (at 1 KHz) by a PCI data acquisition board. This procedure has been repeated 15 times and the mean load at which the cylinder starts to slip is about 16 N. Same measurements have been done with cylinders with larger diameter, representing objects handled in everyday life, 41 mm (225 g) and 71 mm (670 g) resulting in load force values of 36 N and 28 N respectively. Similarly, for the lateral grip (hand grasping a credit card) we measured 8 N (using this time a 2 kg load cell).
The tension figures (all below 70 N) also give a qualitative indication on how far such a condition (7.5 kg load) is from tendon damage, that behaving as a mechanical fuse, represents a safety guard for the hand. Tendons are insured to up to 152 N; this means that the holding load is actually much higher than 7.5 kg. A 10 kg load was actually lifted with the same setup, resulting in no damage for the hand; more accurate stress measurements will be carried out in the future with a more specific setup, being this a non-trivial test to do.
By looking at the graph, some drift is seen in the sensor signals once the load is dropped; this is possibly due to a re-adaptation of the fingers around the handle while it was lifted, resulting in a different (lower energy) final static configuration of the joints. It is interesting to note that the tactile sensor values of the index finger after an initial phase are basically overlapped. This perfectly describes the inherent differential behaviour of the underactuated scheme adopted for the fingers, that tends to distribute torque among links.
The effective usability in domestic environments of innovative brain machine interfaces for prostheses control may be better evaluated (both functionally and cognitively) with tools that allow the user to interact with the environment itself rather than using virtual reality scenarios. To this aim, duplicating the complexity of the entire range of movements of the hand is hard enough provided infinite weight and size, but it needs to be accomplished within a slender morphology, replicating the look and the weight of the human hand. The Anatomically Correct Testbed (ACT)  and the commercially available Shadow robot hand, with their bulky actuation/control units, represent clear examples of such problem. In the constrained volume imposed by the biological model, trade-offs for approximating the natural hand are therefore mandatory. Several self-contained robotic prosthetic hands suitable for a transradial level of amputation have been developed up to now, nonetheless all of them would be rather inappropriate if/when a large bandwidth bi-directional link for control and perception would be available. Therefore, a successful integration of commercial components and state of the art techniques into a working anthropomorphic robotic hand still nowadays represents an open-problem in upper limb prosthetic research. The novelty of this prosthesis compared to previous prototypes and previous authors' work, is that it embeds in 530 g human-sized palm and fingers: (i) a set of non-back-drivable actuators allowing 85% ADLs grips, (ii) a sensory system comprising sensorial information perceivable by the patients using state of the art invasive or non-invasive interfaces [30, 37–39], (iii) a low-power flexible controller able to drive actions and communicate in real time with external brain-machine interfaces. These combined features make the SmartHand prototype a unique robot/instrument for motor control and sensory feedback neuroscientific experiments with upper limb amputees.
Some aspects of the hand may be further discussed. Globally, the achieved mechanical, speed, and grip-power performance are considered satisfactory for the purposes under investigation. The maximum speed for example (closing time 1.5 s), is sufficiently high that patients would need significant training -aided by visual input- for matching the reaching movements of their limbs to the robotic hand speed. The 10 kg suitcase lifted by the hand, represents an interesting figure that robot hand designers should aim to. Regarding the grasping force, the hand was able to stably grasp objects without slippage; however while a 3.6 kg seems to be a sufficiently heavy object to maintain in a power grip prehensile form, an 800 g lateral grip could be inadequate for daily living activities (e.g. in the task of turning a key in a lock). Without replacing the actuation unit, such value may be improved by changing the mechanical architecture of the thumb from Hirose's configuration to a fixed kinematics scheme (as e.g. the Southampton hand finger). Regarding this point, it is important to underline that grasp stability strongly depends also on friction and compliance between materials, therefore, the use of a cosmetic glove would probably improve it. Regarding the weight (530 g) although similar to other multi-fingered commercial and research prostheses, it might become too heavy for the operator, especially once writs, batteries and cosmetic glove are added. The hand would be worn by the operator on the end of a closely fitting external socket (as shown in Figure 6), hence the weight would bear directly onto the skin of the stump. Since the lever-arm created is large the weight can obstruct blood flow in the underlying skin resulting in symptoms ranging from discomfort, to skin breakdown. Additionally heavy prostheses may cause damages to the wearer like elbow and shoulder overuse, rotary cuff problems, neck and back pain. For such reasons, if a more robust version of the SmartHand will be reengineered in the future, significant efforts should be spent to reduce its weight.
In the authors' opinion, robotic researchers should move towards the development of highly dexterous devices not only able to perform actions, but also ready to provide perception by means of a comprehensive artificial sensory system, in order to match the interface requirements and limits. Among the sensory sensations that may be transferred to the amputee by means of an adequate interface, joint position, touch and force sensors are included whereas only the temperature is not. Slippage and palm sensors are not included either but could be embedded in future versions of the hand. Even if currently there is no viable means to transfer all this afferent information to the amputee, guidelines for doing so have been traced , and novel -potentially revolutionizing- interfaces are nowadays currently being investigated [30, 37, 38]. To avoid the situation where the limiting component of the system is the artificial hand, whenever a novel large bandwidth interface will be ready for chronic clinical implantation, robotic research should be already prepared. It is also clear that for a robot, reliability depends on the number of moving parts and wires of the system, therefore a suitable compromise should be found based on the effective amount of information that can travel through the interface.
The authors have presented the design and the performance evaluation of a 16 DoFs self-contained robotic hand to be used as a research tool for neuro-controlled upper limb prosthetics. Motion is generated by 4 brushed DC motors and transmitted to five underactuated fingers by means of non-back-drivable and differential mechanisms. Its actuation distribution allows the hand both to stably perform fundamental grips useful in activities of daily living, to independently point the index and counting. The fingers contain a total of 32 force, position and tactile sensors, and the hand hosts an internal control architecture able to plan grasps and to exchange with the external world proprioceptive and exteroceptive sensory signals. The weight is close to the natural hand weight and comparable to actual commercial prostheses (hand 530 g plus 145 g for the standard wrist attachment). Speed is comparable to commercial prostheses and slippage tests have shown that the hand is able to stably grasp with a cylindrical prehensile pattern and certain friction and geometric conditions up to 3.6 kg objects, nevertheless it is able to lift a 10 kg suitcase.
Future work will address the development of a cosmetic, protective glove in order to improve the aesthetic and grip of the hand. Functionalities will be tested in experimental sessions by amputees using UPIs with different levels of invasiveness, while the long term objective is to connect the hand directly to the human nervous system by means of neural electrodes in order to investigate the effectiveness of establishing an intuitive, bidirectional flow of information between the nervous system of the amputee and the robotic hand.
Authors would like to thank N. Funaro, A. Persichetti, C. Filippeschi, R. Lazzarini, R. Di Leonardo, A. Melani, F. Þorsteinsson, A. Halldorsdottir, and S. P. Murdoch, for their precious help. This work was supported by the SMARTHAND project (NMP4-CT#2006-33423).
- Dillingham TR, Pezzin LE, Mackenzie EJ: Limb Amputation and Limb Deficiency: epidemiology and Recent Trends in the United States. Southern Medical Journal 2002, 95: 875-83.PubMedGoogle Scholar
- Carrozza MC, Massa B, Micera S, Lazzarini R, Zecca M, Dario P: The Development of a Novel Prosthetic Hand - Ongoing Research and Preliminary Results. IEEE/ASME Transactions on Mechatronics 2002, 7: 108-114. 10.1109/TMECH.2002.1011247View ArticleGoogle Scholar
- Atkins DJ, Heard DCY, Donovan WH: Epidemiologic overview of individuals with upper limb loss and their reported research priorities. Journal of Prosthetics and Orthotics 1996, 8: 2-11. 10.1097/00008526-199600810-00003View ArticleGoogle Scholar
- Lundborg G, Rosen B: Sensory substitution in prosthetics. Hand Clinics 2001, 17: 481-488.PubMedGoogle Scholar
- Carrozza MC, Cappiello G, Micera S, Edin BB, Beccai L, Cipriani C: Design of a cybernetic hand for perception and action. Biological Cybernetics 2006, 95: 629-644. 10.1007/s00422-006-0124-2PubMed CentralView ArticlePubMedGoogle Scholar
- Razic D: Kinematics Design of a Multifunctional Hand Prosthesis. Proceedings of the Fourth International Symposium on External Control of Human Extremities, Dubrovnik, Yugoslavia, Yugoslav Committee for Electronics and Automation, 1972Google Scholar
- Herberts P, Almstrom C, Kadefors R, Lawrence PD: Hand Control Via Myoelectric Patterns. Acta Orthopaedica Scandinavica 1973, 44: 389-409. 10.3109/17453677308989075View ArticlePubMedGoogle Scholar
- Light CM, Chappell PH: Development of a lightweight and adaptable multiple-axis hand prosthesis. Med Eng Phys 2000, 22: 679-684. 10.1016/S1350-4533(01)00017-0View ArticlePubMedGoogle Scholar
- Kyberd PJ, Holland OE, Chappell PH, Smith S, Tregdigo R, Bagwell PJ, Snaith M: Marcus: A two degree of freedom hand prosthesis with hierarchical grip control. IEEE Trans Rehabil Eng 1995, 3: 70-76. 10.1109/86.372895View ArticleGoogle Scholar
- Dechev N, Cleghorn WL, Naumann WL: Multiple finger, passive adaptive grasping prosthetic hand. Mechanism and machine theory 2001, 36: 1157-1173. 10.1016/S0094-114X(01)00035-0View ArticleGoogle Scholar
- Massa B, Roccella S, Carrozza MC, Dario P: Design and development of an underactuated prosthetic hand. Proc Intl Conf on Robotics & Automation 2002.Google Scholar
- Carrozza MC, Suppo C, Sebastiani F, Massa B, Vecchi F, Lazzaroni R, Cutkosky MR, Dario P: The SPRING Hand: Development of a Self-Adaptive Prosthesis for Restoring Natural Grasping. Autonomous Robots 2004, 16: 125-141.View ArticleGoogle Scholar
- Pons JL, Rocon E, Ceres R, Reynaerts D, Saro B, Levin S, Van Moorleghem W: The MANUS-HAND Dextrous Robotics Upper Limb Prosthesis: Mechanical and Manipulation Aspects. Autonomous Robots 2004, 16: 143-163.View ArticleGoogle Scholar
- Pylatiuk C, Schulz S, Kargov A, Bretthauer G: Two Multiarticulated Hydraulic Hand Prostheses. Artificial Organs 2004, 28: 980-986. 10.1111/j.1525-1594.2004.00014.xView ArticlePubMedGoogle Scholar
- Carrozza MC, Cappiello G, Stellin G, Zaccone F, Vecchi F, Micera S, Dario P: A Cosmetic Prosthetic Hand with Tendon Driven Under-Actuated Mechanism and Compliant Joints: Ongoing Research and Preliminary Results. Proc Intl Conf on Robotics & Automation 2005.Google Scholar
- Chu JU, Jung JU, Lee YJ: Design and Control of a Multifunction Myoelectric Hand with New Adaptive Grasping and Self-locking Mechanisms. Proc Intl Conf on Robotics & Automation 2008.Google Scholar
- Nightingale JM: Microprocessor control of an artificial arm. Journal of Microcomputer Applications 1985, 8: 167-173. 10.1016/0745-7138(85)90015-6View ArticleGoogle Scholar
- Kyberd PJ, Mustapha N, Carnegie F, Chappell PH: Clinical experience with a hierarchically controlled myoelectric hand prosthesis with vibro-tactile feedback. Prosthetics and Orthotics International 1993, 17: 56-64.View ArticlePubMedGoogle Scholar
- Pons JL, Ceres R, Rocon E, Reynaerts D, Saro B, Levin S, Van Moorleghem W: Objectives and technological approach to the development of the multifunctional MANUS upper limb prosthesis. Robotica 2005, 23: 301-310. 10.1017/S0263574704001328View ArticleGoogle Scholar
- Pylatiuk C, Mounier S, Kargov A, Schulz S, Bretthauer G: Progress in the development of a multifunctional hand prosthesis. Proc IEEE EMBS Int Conf 2004, 2: 4262-4263.Google Scholar
- Cipriani C, Controzzi M, Carrozza MC: Objectives, Criteria and Methods for the Design of the SmartHand Transradial Prosthesis. Robotica 2010, 28: 919-927. 10.1017/S0263574709990750View ArticleGoogle Scholar
- Ishikawa Y, Yu W, Yokoi H, Kakazu Y: Development of robotic hands with an adjustable power transmitting mechanism. In Intelligent Engineering Systems Through Neural Networks. Volume 10. Edited by: Dagli CH, et al. New York: ASME; 2000:631-636.Google Scholar
- Fite KB, Withrow TJ, Shen X, Wait KW, Mitchell JE, Goldfarb M: A Gas-Actuated Anthropomorphic Prosthesis for Transhumeral Amputees. IEEE Transactions on Robotics 2008, 24: 159-169.View ArticleGoogle Scholar
- Dalley SA, Wiste TE, Withrow TJ, Goldfarb M: Design of a multifunctional anthropomorphic prosthetic hand with extrinsic actuation. IEEE/ASME Trans On Mechatronics 2009, 14: 699-706.View ArticleGoogle Scholar
- Defense Advanced Research Project Agency (DARPA), Arlington, VA, USA, Press release of 8 Feb. 2006: DARPA initiates revolutionary prosthetics programs Google Scholar
- Weir R, Mitchell M, Clark S, Puchhammer G, Haslinger M, Grausenburger R, Kumar N, Hofbauer R, Kushnigg P, Cornelius V, Eder M, Eaton H, Wenstrand D: The intrinsic hand - a 22 degree of freedom artificial hand - wrist replacement. Proc Myoelectric Controls/Powered Prosthetics Symposium 2008, 233-237.Google Scholar
- Mitchell M, Weir RF: Development of a clinically viable multifunctional hand prosthesis. Proc Myoelectric Controls/Powered Prosthetics Symposium 2008, 45-49.Google Scholar
- Cipriani C, Zaccone F, Micera S, Carrozza MC: On the Shared Control of an EMG-Controlled Prosthetic Hand: Analysis of User-Prosthesis Interaction. IEEE Transactions on Robotics 2008, 24: 170-184.View ArticleGoogle Scholar
- Cipriani C, Antfolk C, Balkenius C, Rosén B, Lundborg G, Carrozza MC, Sebelius F: A Novel Concept for a Prosthetic Hand with a Bidirectional Interface: A Feasability Study. IEEE Trans Biomedical Engineering 2009, 56: 2739-2743.View ArticleGoogle Scholar
- Rossini PM, Micera S, Benvenuto A, Carpaneto J, Cavallo G, Citi L, Cipriani C, Denaro L, Denaro V, Di Pino G, Ferreri F, Guglielmelli E, Hoffmann KP, Raspopovic S, Rigosa J, Rossini L, Tombini M, Dario P: Double Nerve Intraneural Interface Implant on a Human Amputee for Robotic Hand Control. Clinical Neurophysiology 2010, 121: 777-783. 10.1016/j.clinph.2010.01.001View ArticlePubMedGoogle Scholar
- Controzzi M, Cipriani C, Carrozza MC: Mechatronic Design of a Transradial Cybernetic Hand. IEEE/RSJIntl Conf on Intelligent Robots and Systems 2008.Google Scholar
- Cipriani C, Controzzi M, Vecchi F, Carrozza MC: Embedded Hardware Architecture Based on Microcontrollers for the Action and Perception of a Transradial Prosthesis. IEEE RAS/EMBS Intl Conf on Biomedical Robotics and Biomechatronics 2008.Google Scholar
- Pylatiuk C, Schulz S, Dodelrein L: Results of an internet survey of myoelectric prosthetic hand users. Prosthetic Orthotic Int 2007, 31: 362-370. 10.1080/03093640601061265View ArticleGoogle Scholar
- Sollerman C, Ejeskar A: Sollerman hand function test. A standardized method and its use in tetraplegic patients. Scand J Plast Reconstr Surg Hand Surg 1995, 29: 167-176. 10.3109/02844319509034334View ArticlePubMedGoogle Scholar
- Kamper DG, Cruz EG, Siegel MP: Stereotypical fingertip trajectories during grasp. Journal of Neurophysiology 2003, 90: 3702-3710. 10.1152/jn.00546.2003View ArticlePubMedGoogle Scholar
- Hirose S: Connected differential mechanism and its applications. Proc of the Intl Conf on Advanced Robotics 1985, 319-326.Google Scholar
- Dhillon GS, Horch KW: Direct Neural Sensory Feedback and Control of a Prosthetic Arm. IEEE Trans on Neural Systems and Rehabilitation Engineering 2005, 13: 468-472. 10.1109/TNSRE.2005.856072View ArticlePubMedGoogle Scholar
- Kuiken TA, Marasco PD, Lock BA, Harden RN, Dewald JPA: Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervation. PNAS 2007, 104: 20061-20066. 10.1073/pnas.0706525104PubMed CentralView ArticlePubMedGoogle Scholar
- Ehrsson HH, Rosén B, Stockselius A, Ragnö C, Köhler P, Lundborg G: Upper limb amputees can be induced to experience a rubber hand as their own. Brain 2008, 131: 3443-3452. 10.1093/brain/awn297PubMed CentralView ArticlePubMedGoogle Scholar
- Webster JG: Tactile Sensors for Robotics and Medicine. John Wiley & Sons, New York; 1988.Google Scholar
- Persichetti A, Vecchi F, Carrozza MC: Optoelectronic-based flexible contact sensor for robot finger application. Proc of the Intl Conf on Rehabilitation Robotics 2007.Google Scholar
- Buchholz B, Armstrong TJ, Goldstein SA: Anthropometric data for describing the kinematics of the human hand. Ergonomics 1992, 35: 261-273. 10.1080/00140139208967812View ArticlePubMedGoogle Scholar
- Zollo L, Roccella S, Guglielmelli E, Carrozza MC, Dario P: Biomechatronic Design and Control of an Anthropomorphic Artificial Hand for Prosthetic and Robotic Applications. IEEE/ASME Trans On Mechatronics 2007, 12: 418-429.View ArticleGoogle Scholar
- The i-LIMB hand[http://www.touchbionics.com/i-LIMB]
- Cipriani C, Zaccone F, Stellin G, Beccai L, Cappiello G, Carrozza MC, Dario P: Closed Loop Controller for a Bio-inspired Multi-fingered Underactuated Prosthesis. Proc of IEEE Intl Conf on Robotics and Automation 2006, 2111-2116.Google Scholar
- Controzzi M, Cipriani C, Carrozza MC: Miniaturized non-back-drivable mechanism for robotic applications. Mechanism and Machine Theory 2010 2010, 45: 1395-1406. 10.1016/j.mechmachtheory.2010.05.008View ArticleGoogle Scholar
- Matsuoka Y, Afshar P, Oh M: On the design of robotic hands for brain-machine interface. Neurosurgical Focus 2006, 20: 1-9.View ArticleGoogle Scholar
- Shadow Robot Company[http://www.shadowrobot.com]
- Riso RR: Strategies for providing upper extremity amputees with tactile and hand position feedback - moving closer to the bionic arm. Technology and Health Care 1999, 7: 401-409.PubMedGoogle Scholar
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